Evidence map›Paper›PMID 36762548›Full record

ArticleDrug delivery2023

Andrographolide nanophytosomes exhibit enhanced cellular delivery and pro-apoptotic activities in HepG2 liver cancer cells.

Thikryat Neamatallah, Azizah M Malebari, Abdulmohsin J Alamoudi, Syed Nazreen, Mohammad Mahboob Alam, Hawazen H Bin-Melaih, Osama A Abuzinadah, Shaimaa M Badr-Eldin, Gharam Alhassani, Lamar Makki and 1 more

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Thikryat NeamatallahDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Azizah M MalebariDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Abdulmohsin J AlamoudiDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Syed NazreenDepartment of Chemistry, Faculty of Science, Albaha University, Albaha, Saudi Arabia.
Mohammad Mahboob AlamDepartment of Chemistry, Faculty of Science, Albaha University, Albaha, Saudi Arabia.
Hawazen H Bin-MelaihDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Osama A AbuzinadahDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Shaimaa M Badr-EldinDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Gharam AlhassaniDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Lamar MakkiDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed Z NasrullahDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0002-4755-0742
King Abdulaziz University · SAAl Baha University · SACairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Andrographolide (AG), a major active constituent of

Indexed as

DiterpenesLiver NeoplasmsApoptosisCell ProliferationG2 Phase Cell Cycle CheckpointsHep G2 CellsHumansandrographolideDiterpenesAndrographolideapoptosisHepG2 cellsliver cancerphytosomes

Identifiers

PMID36762548
PMCPMC9930834
OpenAlexW4319826055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.