Evidence map›Paper›PMID 36762331›Full record

ArticleJournal of medicine and life2022

The use of hydrolyzed formulas as a method of correction of feeding and clinical rehabilitation of infants with atopy signs.

Volodymyr Volodymyrovych Bezruk, Oleksii Serhiiovych Godovanets, Oleksandr Hryhorovych Buriak, Nina Ivanivna Voytkevich, Olena Victorivna Makarova, Oksana Ivanivna Yurkiv, Michael Ivanovych Sheremet, Oleksandr Vyacheslavovych Bilookyi, Mykhailo Mykhailovich Hresko, Mariya Ivanivna Velia and 6 more

Abstract read
In one paragraph

Article in Journal of medicine and life, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Volodymyr Volodymyrovych BezrukDepartment of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleksii Serhiiovych GodovanetsDepartment of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleksandr Hryhorovych BuriakDepartment of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine.
Nina Ivanivna VoytkevichDepartment of Foreign Languages, Bukovinian State Medical University, Chernivtsi, Ukraine.
Olena Victorivna MakarovaDepartment of Patient Care and Higher Nursing Education, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oksana Ivanivna YurkivDepartment of Patient Care and Higher Nursing Education, Bukovinian State Medical University, Chernivtsi, Ukraine.
Michael Ivanovych SheremetDepartment of Surgery No.1, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleksandr Vyacheslavovych BilookyiDepartment of Surgery No.1, Bukovinian State Medical University, Chernivtsi, Ukraine.
Mykhailo Mykhailovich HreskoDepartment of Surgery No.1, Bukovinian State Medical University, Chernivtsi, Ukraine.
Mariya Ivanivna VeliaDepartment of Pharmacy, Bukovinian State Medical University, Chernivtsi, Ukraine.
Svyatoslava Vasylivna YurniukDepartment of Pharmacy, Bukovinian State Medical University, Chernivtsi, Ukraine.
Maryna Dmytrivna HreskoDepartment of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine.
Tetiana Sergiivna BulykDepartment of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine.
Larysa Vasylyvna RynzhukDepartment of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleh Olehovich MaksymivDepartment of Prosthetic Dentistry, Bukovinian State Medical University, Chernivtsi, Ukraine.
Igor Dmytrovych ShkrobanetsDepartment of Medical and Organizational Management, National Academy of Medical Sciences of Ukraine, Kiev, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study showed that in formula-fed babies, the use of mixture X (containing 2'-FL (2'-fucosyllactose) - a type of milk oligosaccharide, as well as carefully studied Bifidobacterium lactis, DHA, ARA, and nucleotides) as the main product for feeding could ensure children's body with all the necessary nutrients. Furthermore, it can minimize the progression of clinical signs of atopic dermatitis and reduce the use of drugs. In addition, there was an improvement in height and weight parameters, proportional development of the child (p<0.05), an increase in the number of erythrocytes (erythrocytes), hemoglobin (Hb), mean cell volume (MCV) (p<0.05), a decrease in the number of leukocytes (WBC) (p<0.05), and leveling of skin signs of atopic dermatitis (AD) (according to SCORAD a decrease from 32.8±5.5 to 16.1±2.2, p<0.05). Based on these results, it is possible to recommend using mixture (X) with a preventive and rational purpose as a product of artificial feeding of children with a hereditary predisposition to allergies.

Indexed as

Dermatitis, AtopicChildHumansImmunoglobulin EInfantImmunoglobulin Eatopic dermatitischildrenformula feeding

Identifiers

PMID36762331
PMCPMC9884356

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.