Evidence map›Paper›PMID 36762117›Full record

ArticleFrontiers in pharmacology2023

Characterization of the metabolism of eupalinolide A and B by carboxylesterase and cytochrome P450 in human liver microsomes.

Yingzi Li, Xiaoyan Liu, Ludi Li, Tao Zhang, Yadong Gao, Kewu Zeng, Qi Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The Small Molecule Compound Eupalinolide B Alleviates Neuropathic Pain by Regulating the USP7/Keap1/Nrf2 Pathway.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yingzi LiDepartment of Toxicology, School of Public Health, Peking University, Beijing, China.
Xiaoyan LiuDepartment of Toxicology, School of Public Health, Peking University, Beijing, China.
Ludi LiDepartment of Toxicology, School of Public Health, Peking University, Beijing, China.
Tao ZhangDepartment of Toxicology, School of Public Health, Peking University, Beijing, China.
Yadong GaoDepartment of Toxicology, School of Public Health, Peking University, Beijing, China.
Kewu ZengState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Qi WangDepartment of Toxicology, School of Public Health, Peking University, Beijing, China.
Peking University · CNChina National Center for Food Safety Risk Assessment · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eupalinolide A (EA; Z-configuration) and eupalinolide B (EB; E-configuration) are bioactive cis-trans isomers isolated from

Indexed as

carboxylesteraseCYP phenotypingcytochrome P450enzyme kineticseupalinolide Aeupalinolide Bhuman liver microsomesmetabolic stability

Identifiers

PMID36762117
PMCPMC9905117
OpenAlexW4317888363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.