Evidence map›Paper›PMID 36762110›Full record

ArticleFrontiers in pharmacology2023

Binding and functional structure-activity similarities of 4-substituted 2,5-dimethoxyphenyl isopropylamine analogues at 5-HT

Prithvi Hemanth, Pallavi Nistala, Vy T Nguyen, Jose M Eltit, Richard A Glennon, Małgorzata Dukat

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Potent and Selective Human 5-HTJournal of medicinal chemistry · 2024
    Article
  2. Review
  3. Structure activity relationships of 5-HTEuropean journal of medicinal chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prithvi HemanthDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Pallavi NistalaDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Vy T NguyenDepartment of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Jose M EltitDepartment of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Richard A GlennonDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Małgorzata DukatDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Virginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Certain 4-substituted analogs of 1-(2,5-dimethoxyphenyl)isopropylamine (2,5-DMA) are psychoactive classical hallucinogens or serotonergic psychedelic agents that function as human 5-HT

Indexed as

5-HT2A5-HT2BagonistantagonistCa2+ mobilization assaypsychedelic agentsQSARvalvulopathy

Identifiers

PMID36762110
PMCPMC9902381
OpenAlexW4317908150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.