Evidence map›Paper›PMID 36761498›Full record

ReviewClinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology2023

Knowns and unknowns about congenital hypothyroidism: 2022 update.

Tomoyo Itonaga, Yukihiro Hasegawa, Shinji Higuchi, Mari Satoh, Hirotake Sawada, Kazuhiro Shimura, Ikuko Takahashi, Noriyuki Takubo, Keisuke Nagasaki

Open access · diamondAbstract readReview
In one paragraph

Review in Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 1 country.

Tomoyo ItonagaDepartment of Pediatrics, Oita University Faculty of Medicine, Oita, Japan.
Yukihiro HasegawaDivision of Endocrinology and Metabolism, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Shinji HiguchiDivision of Pediatric Endocrinology and Metabolism, Children's Medical Center, Osaka City General Hospital, Osaka, Japan.
Mari SatohDepartment of Pediatrics, Toho University Omori Medical Center, Tokyo, Japan.
Hirotake SawadaDivision of Pediatrics, Faculty of Medicine, University of Miyazaki Hospital, Miyazaki, Japan.
Kazuhiro ShimuraDepartment of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
Ikuko TakahashiDepartment of Pediatrics, Akita University Graduate School of Medicine, Akita, Japan.
Noriyuki TakuboDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Keisuke NagasakiDepartment of Pediatrics, Niigata University Medical and Dental Hospital, Niigata, Japan.
Akita University · JPJuntendo University · JPKeio University · JPNiigata University Medical and Dental Hospital · JPOita University · JPOsaka City General Hospital · JPToho University · JPTokyo Metropolitan Children's Medical Center · JPUniversity of Miyazaki Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several excellent guidelines and expert opinions on congenital hypothyroidism (CH) are currently available. Nonetheless, these guidelines do not address several issues related to CH in detail. In this review, the authors chose the following seven clinical issues that they felt were especially deserving of closer scrutiny in the hope that drawing attention to them through discussion would help pediatric endocrinologists and promote further interest in the treatment of CH. 1. How high should the levothyroxine (L-T4) dose be for initial treatment of severe and permanent CH? 2. What is the optimal method for monitoring treatment of severe CH? 3. At what level does maternal iodine intake during pregnancy affect fetal and neonatal thyroid function? 4. Does serum thyroglobulin differ between patients with a dual oxidase 2 (

Indexed as

congenital hypothyroidismiodinelevothyroxinemolecular geneticsthe dual oxidase 2 (DUOX2)

Identifiers

PMID36761498
PMCPMC9887299
OpenAlexW4312304143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.