ArticleFrontiers in endocrinology2023
Distribution of microbes and antimicrobial susceptibility in patients with diabetic foot infections in South China.
Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.International wound journal · 2026Pooled it
- Prevalence of multidrug-resistant bacterial infections in diabetic foot ulcers: A meta-analysis.International wound journal · 2024Pooled it
- In Vitro Antibacterial Effect of Probiotics Against Bacterial Isolates from Diabetic Foot Ulcers in Ain Shams University Hospitals.Probiotics and antimicrobial proteins · 2026Article
- Analysis of the species distribution and drug resistance of pathogenic microorganisms causing diabetic foot infections in Southwest China from 2020 to 2024: a retrospective cross-sectional analysis.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Analysis of pathogen distribution and association with lipid levels in patients with diabetic foot.Frontiers in medicine · 2026Article
- Management of Diabetic Foot Infections Using Phage Therapy.Infection and drug resistance · 2026Review
- Antimicrobial resistance profiles and detection of mecA, blaCTX-M-1, and blaSHV genes in bacteria among diabetic foot ulcer patients from selected referral hospitals in Uganda.BMC infectious diseases · 2025Article
- Characterization of Microbial Profiles and Antimicrobial Resistance in Diabetic Foot Ulcers at a Tertiary Care Facility in Northern China.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Natural products in the treatment of diabetic foot infection.European journal of medical research · 2025Review
- The latest research progress on the clinical application of nemonoxacin.Frontiers in medicine · 2025Review
- Deciphering microbiome and fungi-bacteria interactions in chronic wound infections using metagenomic sequencing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Bacterial profile and antimicrobial resistance patterns of infected diabetic foot ulcers in low- and middle-income countries: a systematic review and meta‑analysis.Therapeutic advances in infectious diseaseReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To investigate the distribution of microbes and drug susceptibility in patients with diabetic foot infections (DFI) and provide guidance for clinical empirical treatment and the rational selection of antibacterial drugs. Methods: Retrospective analysis of the pathogenic bacterium distribution and antimicrobial susceptibility isolated from 581 DFI patients with different Wagner grades. Results: The 534 positive samples included 473 cases (88.58%)) of monomicrobial infections and 61 cases (11.42%) of polymicrobial infections before antibiotic therapy. A total of 656 strains were cultivated, including 387 (58.99%) strains of gram-positive organisms (GPOs), 235 (35.82%) gram-negative bacilli (GNB), and 21 (3.20%) fungal strains. Polymicrobial infections mainly occurred in patients with Wagner grade 3-4 ulcers. GPOs were predominant in Wagner grades 1-3 (grade 1: 96.67%, grade 2: 76.52%, grade 3 62.81%), and the most common was Staphylococcus aureus (grade 1: 31.66%, grade 2: 33.04%, grade 3 35.53%). GNB were predominant in grades 4-5 (grade 4: 51.46%, grade 5:60%), and the most common GNB in Wagner grades 4-5 was Conclusion: The distribution of microbes and antimicrobial susceptibility in DFI patients varied with different Wagner grades. The most appropriate antimicrobial therapy should be selected based on the pathogen culture and antimicrobial susceptibility.
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