Evidence map›Paper›PMID 36761129›Full record

ArticleFrontiers in public health2023

Risk of peripheral facial palsy following parenteral inactivated influenza vaccination in the elderly Chinese population.

Tianchi Yang, Rui Ma, Lixia Ye, Qiuhong Mei, Jianmei Wang, Yueyi Feng, Shaoying Zhou, Xingqiang Pan, Danbiao Hu, Dandan Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tianchi YangImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Rui MaImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Lixia YeImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Qiuhong MeiImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Jianmei WangImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Yueyi FengImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Shaoying ZhouImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Xingqiang PanImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Danbiao HuImmunization Center, Ninghai County Center for Disease Control and Prevention, Ningbo, China.
Dandan ZhangImmunization Center, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Ningbo Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Concern about the risk of peripheral facial palsy (PFP) following vaccination is one reason for hesitancy in influenza vaccination. However, the association between the flu vaccine and PFP is still controversial, and further evidence is urgently needed. Methods: This self-controlled case series study evaluated PFP risk following inactivated influenza vaccine in the elderly using a large linked database in Ningbo, China. Relative incidence ratios (RIRs) and 95% confidence intervals (CIs) estimated using conditional Poisson regression were utilized to determine whether the risk of PFP was increased after vaccination. Results: This study included 467 episodes, which occurred in 244 females and 220 males. One hundred twenty-four episodes happened within 1-91 days after vaccination, accounting for 26.7%. The adjusted RIRs within 1-30 days, 31-60 days, 61-91 days, and 1-91 days after influenza vaccination were 0.95 (95% CI 0.69-1.30), 1.08 (95% CI 0.78-1.49), 1.01 (95% CI 0.70-1.45), and 1.00 (95% CI 0.81-1.24), respectively. Similar results were found in subgroup analyses and sensitivity analyses. Conclusions: Influenza vaccination does not increase PFP risk in the elderly population. This finding provides evidence to overcome concerns about facial paralysis after influenza vaccination.

Indexed as

Facial ParalysisInfluenza, HumanInfluenza VaccinesAgedEast Asian PeopleFemaleHumansMaleVaccinationVaccines, InactivatedInfluenza VaccinesVaccines, Inactivatedelderlyinactivated influenza vaccinationperipheral facial palsyrelative incidence ratioself-controlled case series study

Identifiers

PMID36761129
PMCPMC9902766
OpenAlexW4317886269

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.