ReviewFrontiers in aging neuroscience2022
Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly.
Review in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Effects of different types of Tai Chi intervention on motor function in older adults: a systematic review.Aging clinical and experimental research · 2025Pooled it
- Effects of Tai Chi Chuan on cognitive function in adults 60 years or older with mild cognitive impairment: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Effects of traditional Chinese exercises or their integration with medical treatments on cognitive impairment: a network meta-analysis based on randomized controlled trials.Frontiers in aging neuroscience · 2024Pooled it
- The effectiveness of Tai Chi for patients with mild cognitive impairment: a systematic review and meta-analysis.Frontiers in neuroscience · 2024Pooled it
- The effects of different types of Tai Chi exercise on anxiety and depression in older adults: a systematic review and network meta-analysis.Frontiers in public health · 2023Pooled it
- A randomized controlled trial to unveil the influence of an exercise intervention on brain integrity and gut microbiome structure in individuals with HIV.AIDS (London, England) · 2026Trial
- Trial
- Effects of Tai Chi combined with tDCS on cognitive function in patients with MCI: a randomized controlled trial.Frontiers in public health · 2023Trial
- Comparative effects of Baduanjin and square dance on working memory, executive function performance, mood, and fatigue in older women: a randomized controlled trial.Frontiers in psychology · 2026Article
- Lifestyle interventions for dementia risk reduction: A review on the role of physical activity and diet in Western and Asian Countries.The journal of prevention of Alzheimer's disease · 2025Review
- The Impact of Long-Term Tai Chi Practice on the Trust Behavior of Middle-Aged People.Brain and behavior · 2025Article
- Tai Chi Practice Buffers Aging Effects in Functional Brain Connectivity.Brain sciences · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mild cognitive impairment (MCI) is a major public health concern that endangers health and decreases the quality of life of the elderly around the world. A recent clinical guideline has recommended regular exercise (twice per week) for patients with MCI as part of an overall approach to management. Tai Chi, a form of light-to-moderate-intensity mind-body exercise, is particularly suitable for seniors. This review aims to summarize epidemiological studies related to the effects of Tai Chi on symptom remission in older adults with MCI and reveal the potential mechanisms. Evidence suggested that Tai Chi can improve cognitive functions and alleviate the accompanying symptoms of MCI in the elderly potentially by activating the expression of signals in different brain regions, altering their connectivity, increasing the brain volume, and modulating brain-derived neurotropic and inflammation factors. Studies comparing various types of Tai Chi may contribute to the identification of paradigms that have appropriate intensities and difficulty and exert good effects on older people with MCI. In addition, studies are warranted to determine the frequency and duration of training that can optimize the beneficial effects of Tai Chi on MCI.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.