ArticleFrontiers in microbiology2023
The fate of sulfonamide resistance genes and anthropogenic pollution marker
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 40 citations in OpenAlex.
- Detection and removal methods of antibiotic-resistance genes in drinking water sources: a review.Journal of water and health · 2026Review
- The Fate of Antibiotic Resistance Genes and Their Influential Factors During Large-Scale Cattle Manure Composting.Toxics · 2026Article
- Fate of the resistance profile of drinking water biofilm exposed to a sub-minimum inhibitory concentration of ciprofloxacin.npj antimicrobials and resistance · 2026Article
- Microplastics and intI1 antibiotic resistance-associated marker in rural water systems: an exploratory GIS-based environmental assessment.Frontiers in microbiology · 2026Article
- Diverse enteric bacterial, viral, and parasitic pathogen genes are shed in animal feces in Indiana.PloS one · 2026Article
- Genomic and phylogeographical analysis revealed CTX-M-55 producingOne health (Amsterdam, Netherlands) · 2025Article
- Development and application of a highly sensitive quadruple droplet digital PCR method for simultaneous quantification of sulfonamide resistance genes.Frontiers in microbiology · 2025Article
- Riverine antibiotic resistome along an anthropogenic gradient.Frontiers in microbiology · 2025Article
- Unseen Weapons: Bacterial Extracellular Vesicles and the Spread of Antibiotic Resistance in Aquatic Environments.International journal of molecular sciences · 2024Review
- Genome-centric analyses of 165 metagenomes show that mobile genetic elements are crucial for the transmission of antimicrobial resistance genes to pathogens in activated sludge and wastewater.Microbiology spectrum · 2024Article
- Surfaces of gymnastic equipment as reservoirs of microbial pathogens with potential for transmission of bacterial infection and antimicrobial resistance.Frontiers in microbiology · 2023Article
- Antibiotic resistance indicator genes in biofilm and planktonic microbial communities after wastewater discharge.Frontiers in microbiology · 2023Article
- Holistic analysis of sustainable waste streams used as lettuce fertilizers applied individually and in combinations.Journal of environmental qualityArticle
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Currently there are sparse regulations regarding the discharge of antibiotics from wastewater treatment plants (WWTP) into river systems, making surface waters a latent reservoir for antibiotics and antibiotic resistance genes (ARGs). To better understand factors that influence the fate of ARGs in the environment and to foster surveillance of antibiotic resistance spreading in such habitats, several indicator genes have been proposed, including the integrase gene Methods: Here we used quantitative PCR and long-read nanopore sequencing to monitor the abundance of these indicator genes and ARGs present as class 1 integron gene cassettes in a river system from pristine source to WWTP-impacted water. ARG abundance was compared with the dynamics of the microbial communities determined Results: Our results show that WWTP effluent was the principal source of all three sulfonamides with highest concentrations for SMX (median 8.6 ng/l), and of the indicator genes Discussion: We found no evidence that low amounts of sulfonamides in the aquatic environment stimulate the maintenance or even spread of corresponding ARGs. Nevertheless, class 1 integrons carrying various ARGs were still present 13 km downstream from the WWTP. Therefore, limiting the release of ARG-harboring microorganisms may be more crucial for restricting the environmental spread of antimicrobial resistance than attenuating ng/L concentrations of antibiotics.
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