Evidence map›Paper›PMID 36760465›Full record

ArticleCase reports in gastroenterology

Colonic Dilatation Complicating Acute Severe Ulcerative Colitis Managed Successfully with Accelerated Infliximab Dosing.

Hoang Huu Bui, Luan Minh Dang, Diem Thi-Ngoc Vo, Chuong Dinh Nguyen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hoang Huu BuiDepartment of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Luan Minh DangDepartment of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Diem Thi-Ngoc VoDepartment of Pathology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Chuong Dinh NguyenDepartment of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
University of Medicine and Pharmacy at Ho Chi Minh City · VNUniversity Medical Center HCMC · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lately, emerging data suggest an association between the development of inflammatory bowel disease and anti-interleukin-17 therapy. Megacolon is a life-threatening complication of acute severe ulcerative colitis (ASUC), but its treatment has not yet been established in current practice guidelines. We report a rare case of known psoriasis treated by secukinumab in a patient who presented with ASUC and colonic dilatation. Neither steroids nor standard infliximab regimen was effective. Finally, rescue therapy with accelerated infliximab strategy resulted in excellent recovery. In certain cases of steroid-refractory ASUC complicated by megacolon, accelerated infliximab regimen can be an alternative to surgery.

Indexed as

Accelerated infliximab regimenAcute severe ulcerative colitisAnti-interleukin-17 agentsColonic dilatation

Identifiers

PMID36760465
PMCPMC9906040
OpenAlexW4319337134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.