Evidence map›Paper›PMID 36760460›Full record

ArticleHealth services insights2023

Healthcare Costs and Health-Related Quality of Life in Older Multimorbid Patients After Hospitalization.

Paola Salari, Séverine Henrard, Cian O'Mahony, Paco Welsing, Arjun Bhadhuri, Katharina Tabea Jungo, Thomas Beck, Denis O'Mahony, Stephen Byrne, Anne Spinewine and 3 more

Open access · goldAbstract read
In one paragraph

Article in Health services insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Hospital Cost Components and Predictors inTropical medicine and infectious disease · 2026
    Article
  3. Analysing the impact of complex multimorbidity on health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  4. Article
  5. Observational
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Paola SalariInstitute of Pharmaceutical Medicine (ECPM), University of Basel, Switzerland.ORCID https://orcid.org/0000-0003-3757-6081
Séverine HenrardLouvain Drug Research Institute, Clinical Pharmacy Research Group, UCLouvain, Brussels, Belgium.
Cian O'MahonyPharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork University Hospital, Ireland.
Paco WelsingDivision of Internal Medicine and Dermatology, University Medical Centre Utrecht, The Netherlands.
Arjun BhadhuriInstitute of Pharmaceutical Medicine (ECPM), University of Basel, Switzerland.
Katharina Tabea JungoInstitute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Thomas BeckDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Denis O'MahonyDepartment of Medicine (Geriatrics), University College Cork, Cork University Hospital, Cork, Ireland.
Stephen ByrnePharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork University Hospital, Ireland.
Anne SpinewineLouvain Drug Research Institute, Clinical Pharmacy Research Group, UCLouvain, Brussels, Belgium.
Wilma KnolDepartment of Geriatric Medicine and Expertise Centre Pharmacotherapy in Old Persons, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.
Nicolas RodondiInstitute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Matthias SchwenkglenksInstitute of Pharmaceutical Medicine (ECPM), University of Basel, Switzerland.
University College Cork · IEUniversity of Basel · CHUniversity of Bern · CHSolvay (Belgium) · BEUniversity Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We identified factors associated with healthcare costs and health-related quality of life (HRQoL) of multimorbid older adults with polypharmacy. Methods: Using data from the OPERAM (OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid older people) trial, we described the magnitude and composition of healthcare costs, and time trends of HRQoL, during 1-year after an acute-care hospitalization. We performed a cluster analysis to identify groups with different cost and HRQoL trends. Using multilevel models, we also identified factors associated with costs and HRQoL. Results: Two months after hospitalization monthly mean costs peaked (CHF 7'124) and HRQoL was highest (0.67). They both decreased thereafter. Age, falls, and comorbidities were associated with higher 1-year costs. Being female and housebound were negatively associated with HRQoL, while moderate alcohol consumption had a positive association. Being independent in daily activities was associated with lower costs and higher HRQoL. Conclusion: Although only some identified potential influences on costs and HRQoL are modifiable, our observations support the importance of prevention before health deterioration in older people with multimorbid illness and associated polypharmacy.

Indexed as

elderlyhealthcare costsHRQoLmultimorbidity

Identifiers

PMID36760460
PMCPMC9903041
OpenAlexW4319321554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.