Evidence map›Paper›PMID 36760308›Full record

ArticleRSC advances2023

Aza-Michael promoted glycoconjugation of PETIM dendrimers and selectivity in mycobacterial growth inhibitions.

Biswajit Sarkar, Avisek Mahapa, Kalyan Dey, Rakshit Manhas, Dipankar Chatterji, Narayanaswamy Jayaraman

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Biswajit SarkarDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560 012 India jayaraman@iisc.ac.in.
Avisek MahapaMolecular Biophysics Unit, Indian Institute of Science Bangalore 560 012 India dipankar@iisc.ac.in.
Kalyan DeyDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560 012 India jayaraman@iisc.ac.in.
Rakshit ManhasInfectious Disease Department, CSIR-Indian Institute of Integrative Medicine Jammu-180001 India avisek.mahapa@gmail.com.
Dipankar ChatterjiMolecular Biophysics Unit, Indian Institute of Science Bangalore 560 012 India dipankar@iisc.ac.in.
Narayanaswamy JayaramanDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560 012 India jayaraman@iisc.ac.in.ORCID https://orcid.org/0000-0001-5577-8053
Indian Institute of Science Bangalore · INIndian Institute of Integrative Medicine · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The benign nature of aza-Michael addition reaction in aqueous solutions is demonstrated herein to conduct a direct glycoconjugation of amine-terminated poly(ether imine) (PETIM) dendrimers. Zero to three generations of dendrimers, possessing up to 16 amine functionalities at their peripheries, undergo aza-Michael reaction with unsaturated sugar vinyl sulfoxide in aq. MeOH solutions and afford the corresponding dendrimers modified with multiple glycosyl moieties at the periphery. First order kinetics of the glycoconjugation is monitored at varying temperatures and the rate constants are observed to be 60-508 s

Identifiers

PMID36760308
PMCPMC9897202
OpenAlexW4319078545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.