Evidence map›Paper›PMID 36759913›Full record

ArticleJournal of medical case reports2023

Extramedullary relapse of Immunoglobulin A-kappa myeloma manifesting as plasmacytoma of the pleura without bone marrow involvement and following autologous bone marrow transplant: a case report.

Alireza Rezvani, Reza Shahriarirad, Mohammad Javad Fallahi, Ali Zeighami

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alireza RezvaniBone Marrow Transplantation Center, Nemazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Reza ShahriariradThoracic and Vascular Surgery Research Center, Shiraz University of Medical Science, Shiraz, 71936-13311, Iran.
Mohammad Javad FallahiDepartment of Internal Medicine, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali ZeighamiThoracic and Vascular Surgery Research Center, Shiraz University of Medical Science, Shiraz, 71936-13311, Iran. ali.zeighami2009@gmail.com.
Shiraz University · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrence of multiple myeloma is among the most challenging issues for patients and treating physicians reported after autologous stem cell transplantation. However, extramedullary involvement after chemotherapy and transplantation has been rarely reported, especially as pleural manifestations. Protein electrophoresis indicated immunoglobulin A monoclonal kappa plasma cell neoplasm in our case. CASE PRESENTATION: A 48-year-old middle-eastern man was referred to our clinic with cough, dyspnea, fever, and left side pleural effusion. A year after chemotherapy and autologous bone marrow transplantation, the patient presented with features in favor of pleural relapse, without bone marrow involvement. Protein electrophoresis demonstrated immunoglobulin A monoclonal kappa plasma cell neoplasm in our case. The patient was effectively treated with dexamethasone, thalidomide, cisplatin, doxorubicin, cyclophosphamide, and etoposide with no notable adverse effects.

conclusionPhysicians should be aware of various presentations of multiple myeloma relapse, especially in autologous stem cell transplantation patients. Atypical and unique presentations such as the pleural involvement warrant further reporting of evidence to provide early management and treatment options.

Indexed as

Hematopoietic Stem Cell TransplantationMultiple MyelomaPlasmacytomaAntibodies, MonoclonalBone MarrowBone Marrow TransplantationChronic DiseaseHumansImmunoglobulin AMaleMiddle AgedNeoplasm Recurrence, LocalPleuraTransplantation, AutologousAntibodies, MonoclonalImmunoglobulin ABone marrow transplantationCase reportMultiple myelomaPleural effusionRecurrence

Identifiers

PMID36759913
PMCPMC9912644
OpenAlexW4319659918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.