Evidence map›Paper›PMID 36759868›Full record

ArticleStem cell research & therapy2023

ABCB5

Kaixuan Yan, Jiaxing Zheng, Mark Andreas Kluth, Lin Li, Christoph Ganss, Benito Yard, Richard Magdeburg, Markus H Frank, Prama Pallavi, Michael Keese

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Kaixuan YanDepartment of Surgery, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Jiaxing ZhengDepartment of Surgery, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Mark Andreas KluthTICEBA GmbH, Heidelberg, Germany.
Lin LiDepartment of Surgery, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Christoph GanssTICEBA GmbH, Heidelberg, Germany.
Benito YardV Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Richard MagdeburgDepartment of Surgery, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68161, Mannheim, Germany.
Markus H FrankDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Prama Pallavi *Department of Surgery, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. prama.pallavi@medma.uni-heidelberg.de.ORCID 0000-0001-7788-6645
Michael Keese *Department of Surgery, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Michael.keese@umm.de.
Heidelberg University · DEEdith Cowan University · AURheacell (Germany) · DEUniversity of Mannheim · DE

Funding

Stem Cell Integral Membrane Transporter ABCB5 and Dermal RegenerationP01AG071463 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI GEORGE F MURPHY · 2022 to 2026
$13.6M
ABCB5-positive stem cells for LSCD therapyR01EY025794 · NEI · BOSTON CHILDREN'S HOSPITAL · PI NATASHA Y FRANK, Markus H. Frank · 2016 to 2026
$6.1M
Multipotent ABCB5-positive cell therapeutics for corneal diseaseR24EY028767 · NEI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRANK, MARKUS H., FRANK, NATASHA Y · 2018 to 2022
$5.9M
Skin-Intrinsic Immunosuppressive Mesenchymal Stem Cells and aGVHDR01HL161087 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRANK, MARKUS H., FRANK, NATASHA Y · 2022 to 2025
$1.7M
NEI NIH HHS R01 EY025794NEI NIH HHS R24 EY028767NHLBI NIH HHS R01 HL161087NIA NIH HHS P01 AG071463
6 · The paper itself

Abstract

backgroundHypoxia in ischemic disease impairs Ca

methodsHypoxia was induced in HUVECs by Cobalt (II) chloride (CoCl

resultsHypoxia-induced impairment of cytosolic and ER Ca

conclusionsABCB5

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsATP Binding Cassette Transporter, Subfamily BCalciumCells, CulturedHomeostasisHumansHuman Umbilical Vein Endothelial CellsHypoxiaIschemiaMiceNeovascularization, PhysiologicABCB5 protein, humanATP Binding Cassette Transporter, Subfamily BCalciumAngiogenesisCalcium ionEndothelial cellsHypoxiaMesenchymal stromal cellsPeripheral artery diseaseStem cell therapy

Identifiers

PMID36759868
PMCPMC9912525
OpenAlexW4319722940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.