Evidence map›Paper›PMID 36759846›Full record

ArticleCancer cell international2023

Study on the correlation between B vitamins and breast cancer.

Siqi Xie, Mingjian Tan, Hongwan Li, Lv Li, Hengyu Zhang, Qing Wang, Sijia Li, Jiali Yang, Haoling Xie, Pengyan Chen and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer cell international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Siqi Xie *Department of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Mingjian Tan *Department of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Hongwan Li *Department of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Lv LiInstitute of Oncology, Yunnan Cancer Hospital, The Third Afliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Hengyu ZhangDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Qing WangDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Sijia LiDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Jiali YangDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Haoling XieDepartment of Oncology, Anning First People's Hospital, Kunming, Yunnan Province, China.
Pengyan ChenDepartment of gynecology, Kaiyuan People's Hospital, Kaiyuan, Yunnan Province, China.
Dequan LiuDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China. liu_dequan2018@126.com.
Rong GuoDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China. guorong2320@126.com.
Shicong TangDepartment of Breast Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People's Republic of China. tang_shicong@126.com.ORCID http://orcid.org/0000-0002-0666-5172
Kunming Medical University · CNFirst People's Hospital of Yunnan Province · CN

Funding

National Natural Science Foundation of China 81960517National Natural Science Foundation of China grant no. 81960542Science and Technology Project of Yunnan Provincial Science and Technology Department 202001AU070093Science and Technology Project of Yunnan Provincial Science and Technology Department 202201AY070001-169Science and Technology Project of Yunnan Provincial Science and Technology Department grant no. 202001AU070053
6 · The paper itself

Abstract

backgroundRelevant studies suggest that serum vitamin level is related to the risk of breast cancer, and dietary pattern and drug supplementation can significantly affect the level of vitamin in the body. Therefore, intervention of vitamin level in the body is expected to be a potential strategy to reduce the risk of breast cancer. However, the current epidemiological findings of serum vitamin levels and breast cancer risk are inconsistent, and the relationship between serum vitamin and breast cancer is still controversial. In this study, we compared the serum vitamin expression levels of healthy people, benign breast patients, and breast cancer patients, and evaluated the relationship between B vitamin levels and breast cancer risk.

methodsThe study used liquid chromatography-tandem mass spectrometry to determine the serum vitamin levels of 520 people who attended Yunnan Cancer Hospital from September 2020 to December 2020. After screening by exclusion criteria, 38 patients with benign breast diseases, 87 patients with breast cancer and 91 healthy controls were finally included. The kruskal-wallis H test was used to compare the differences in serum vitamin levels of subjects. Χ

conclusionThe levels of VitB1 and VitB5 in the serum of breast cancer patients and patients with benign breast diseases were higher than those in the healthy control group, while the expression levels of VitB3 in breast cancer patients were lower than those in the healthy control group and the breast benign disease groups. The level of VitB1 was positively correlated with breast cancer risk. The VitB3 level was negatively correlated with breast cancer risk. The VitB5 level is not significantly related to the risk of breast cancer.

Indexed as

Benign breast diseasesBreast cancerB vitamins

Identifiers

PMID36759846
PMCPMC9912611
OpenAlexW4319726986

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.