Evidence map›Paper›PMID 36759843›Full record

ArticleMicrobial cell factories2023

Developing a single-stage continuous process strategy for vitamin B

Álvaro Calvillo, Teresa Pellicer, Marc Carnicer, Antoni Planas

Open access · goldAbstract read
In one paragraph

Article in Microbial cell factories, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Fermentative production of vitamin BFood science & nutrition · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Álvaro CalvilloLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain.ORCID http://orcid.org/0000-0001-9816-8511
Teresa PellicerHealthTech Bio Actives, 08029, Barcelona, Spain.ORCID http://orcid.org/0000-0002-1986-2765
Marc CarnicerLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain. marc.carnicer@iqs.url.edu.ORCID http://orcid.org/0000-0003-4459-5969
Antoni PlanasLaboratory of Biochemistry, Institut Químic de Sarrià, University Ramon Llull, 08017, Barcelona, Spain. antoni.planas@iqs.url.edu.ORCID http://orcid.org/0000-0001-7073-3320
Institut Químic de Sarrià · ES

Funding

Generalitat de Catalunya 2017SGR-727Ministerio de Ciencia e Innovación PID2019-104350RB-I00
6 · The paper itself

Abstract

backgroundVitamin B

resultsInitial results established that: (i) agitation during the early stages of the culture had an inhibitory effect on the volumetric production, (ii) 5,6-dimethylbenzimidazole (DMBI) addition was necessary for vitamin B

conclusionOverall, compared to previously reported strategies aimed to reduce propionic acid inhibition, a less complex anaerobic single-phase continuous and more scalable bioprocess was achieved.

Indexed as

Propionibacterium freudenreichiiFermentationPropionatesPropionibacteriumVitamin B 12VitaminsPropionatespropionic acidVitamin B 12VitaminsCobalaminContinuous cultureCyanocobalamin productionFed-batch culturePropionibacterium freudenreichii

Identifiers

PMID36759843
PMCPMC9912679
OpenAlexW4319734523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.