ArticleBMC ophthalmology2023
Association of chorioretinal thickness with chronic kidney disease.
Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 12 citations in OpenAlex.
- Retinal and choroidal microvascular changes in hemodialysis and peritoneal dialysis: a comparative OCT and OCTA study.International ophthalmology · 2026Observational
- Clinical Anterior Segment and Ocular Surface Findings Across Renal Replacement Modalities: Associations with CKD-Related Factors, Mineral Metabolism and Activin A.Life (Basel, Switzerland) · 2026Article
- Investigation of the association between retinal microcirculation and renal function in children with lupus nephritis.Clinical rheumatology · 2026Article
- Haemodialysis-Induced Stress Influences Ocular Microcirculation.Biomedicines · 2026Article
- Optical Coherence Tomography and Optical Coherence Tomography-Angiography Chronic Changes in End-Stage Renal Disease: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Extracellular fluid excess linked to reduced choroidal vascularity index in patients with chronic kidney disease.Scientific reports · 2024Article
- Looking into the Eyes to See the Heart of Chronic Kidney Disease Patients.Life (Basel, Switzerland) · 2024Article
- The Impact of a Single Haemodialysis Session on the Retinal Thickness and Optic Nerve Morphology.Diagnostics (Basel, Switzerland) · 2024Article
- Retinal nerve fiber layer defects and chronic kidney disease: the Kailuan Eye Study.International journal of ophthalmology · 2024Article
- The Haemodialysis Session Effect on the Choroidal Thickness and Retinal and Choroidal Microcirculation-A Literature Review.Journal of clinical medicine · 2023Review
- Optical Coherence Tomography (OCT): A Brief Look at the Uses and Technological Evolution of Ophthalmology.Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess retinal and choroidal thickness changes in chronic kidney disease (CKD) patients using spectral domain optical coherence tomography (SD-OCT).
backgroundCKD is a devastating health trouble. The eye and the kidney share similar structural and genetic pathways, so that kidney disease and ocular disease may be closely linked. OCT is a precise, fast method for high-definition scanning of the retina and choroid. PATIENTS AND
methodsA cross sectional study was conducted at Menoufia University Hospital ophthalmology department on 144 eyes of 72 CKD patients divided into 3 groups according to the stage of CKD as follows: group 1: CKD stage 1-2, with Glomerular Filtration Rate (GFR) > 60 ml/min/1.73m
resultsRetinal and choroidal thickness were reduced in group 2 (CKD stage 3) and group 3 (CKD stage 4-5) compared with group 1 (CKD stage 1-2). The reduction was more severe in group 3 than group 2. RNFL thickness did not differ between groups. A thinner retina and choroid were associated with an elevated serum C-reactive protein (CRP) concentration, and greater degrees of proteinuria.
conclusionChorioretinal thinning in CKD is associated with a lower eGFR, a higher CRP, and greater proteinuria. Further studies, in a large scale of patients, are needed to detect whether these eye changes reflect the natural history of CKD.
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