Evidence map›Paper›PMID 36759394›Full record

ArticleAIDS and behavior2023

Fertility Desire and Associations with Condomless Sex, Antiretroviral Adherence, and Transmission Potential in a Cohort of Kenyan Women Living with HIV in Sero-discordant Relationships: A Mixed Methods Study.

McKenna C Eastment, John Kinuthia, Kenneth Tapia, George Wanje, Katherine Wilson, Anne Kaggiah, Jane M Simoni, Kishorchandra Mandaliya, Danielle N Poole, Barbra A Richardson and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

McKenna C EastmentDepartment of Medicine, University of Washington, 325 9th Ave, Box 359909, Seattle, WA, 98104, USA. mceast@uw.edu.ORCID http://orcid.org/0000-0002-9185-0902
John KinuthiaDepartment of Global Health, University of Washington, Seattle, WA, USA.
Kenneth TapiaDepartment of Global Health, University of Washington, Seattle, WA, USA.
George WanjeDepartment of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya.
Katherine WilsonDepartment of Global Health, University of Washington, Seattle, WA, USA.
Anne KaggiahKenyatta National Hospital, Nairobi, Kenya.
Jane M SimoniDepartment of Global Health, University of Washington, Seattle, WA, USA.
Kishorchandra MandaliyaDepartment of Global Health, University of Washington, Seattle, WA, USA.
Danielle N PooleDepartment of Geography, Dartmouth College, Hanover, NH, USA.
Barbra A RichardsonDepartment of Global Health, University of Washington, Seattle, WA, USA.
Walter JaokoDepartment of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya.
Grace John-StewartDepartment of Medicine, University of Washington, 325 9th Ave, Box 359909, Seattle, WA, 98104, USA.
R Scott McClellandDepartment of Medicine, University of Washington, 325 9th Ave, Box 359909, Seattle, WA, 98104, USA.
University of Washington · USUniversity of Nairobi · KEDartmouth College · USKenyatta National Hospital · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2021 to 2024
$5.8M
Women's Life Events & HIV Transmission Potential: A Multidisciplinary StudyR01HD072617 · NICHD · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, RAYMOND SCOTT · 2012 to 2016
$2.1M
RCT of an Implementation Science Tool to Integrate HIV testing into Family Planning Services K24HD088229 · NICHD · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, RAYMOND SCOTT · 2016 to 2020
$863k
Randomized controlled trial of an implementation science tool to increase cervical cancer screening in Mombasa, KenyaK08CA228761 · NCI · UNIVERSITY OF WASHINGTON · PI EASTMENT, MCKENNA CLAIRE · 2018 to 2022
$756k
NCI NIH HHS K08 CA228761NIAID NIH HHS P30 AI027757NIAID NIH HHS T32 AI007140NICHD NIH HHS K24 HD088229NICHD NIH HHS R01 HD072617NIMH NIH HHS MH123248NIMH NIH HHS P30 MH123248
6 · The paper itself

Abstract

For women living with HIV (WLH) in serodiscordant partnerships, decisions about childbearing can challenge condom use and antiretroviral adherence. In a prospective cohort of 148 WLH in serodiscordant partnerships, 58 (39%) wanted more children in the future but were not currently trying to conceive (fertility desire), and 32 (22%) were currently trying to become pregnant (fertility intent). Detection of prostate specific antigen (PSA) in vaginal secretions, a marker for recent condomless sex, was lowest in women with fertility desire and highest in women with fertility intent. Detectable viral load followed a similar pattern. Risk of HIV transmission, when condomless sex and PSA detection occurred concurrently, was three to fourfold higher at visits with fertility intent compared to visits with fertility desire. Qualitative interviews underscored the importance women place on childbearing and suggested that they had limited information about the role of antiretroviral therapy in reducing sexual HIV transmission.

Indexed as

HIV InfectionsUnsafe SexAnti-Retroviral AgentsChildFemaleFertilityHumansKenyaMalePregnancyProspective StudiesProstate-Specific AntigenSexual PartnersAnti-Retroviral AgentsProstate-Specific AntigenFertility desireFertility intentSero-discordant partnershipsWomen living with HIV

Identifiers

PMID36759394
PMCPMC10338402
OpenAlexW4319827491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.