Evidence map›Paper›PMID 36759371›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Noninvasive evaluation of PD-L1 expression in non-small cell lung cancer by immunoPET imaging using an acylating agent-modified antibody fragment.

Yuan Cheng, Dai Shi, Renjie Ye, Wenhui Fu, Pengcheng Ma, Zhan Si, Zhan Xu, Lixin Li, Qingyu Lin, Dengfeng Cheng

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuan Cheng *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Dai Shi *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Renjie YeDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Wenhui FuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Pengcheng MaDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Zhan SiDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Zhan XuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Lixin LiDepartment of Hepatic Oncology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China.
Qingyu LinDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China. lin.qingyu@zs-hospital.sh.cn.
Dengfeng ChengDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, China. cheng.dengfeng@zs-hospital.sh.cn.ORCID 0000-0003-2886-3273

Funding

National Natural Science Foundation of China 11875114National Natural Science Foundation of China 82172002National Natural Science Foundation of China 82272058Shanghai Municipal Science and Technology Committee of the Shanghai Outstanding Young Academic Leaders Plan 21XD1423500Zhongshan Hospital, Fudan university 2020ZSLC20
6 · The paper itself

Abstract

purposeThe aim of this study was to explore an effective

methodsThe prepared durva F(ab')

resultsAfter being modified with SHPP, the average conjugation number of SHPP per durva-F(ab')

conclusionsA PD-L1 PET imaging probe [

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsB7-H1 AntigenHumansImmunoglobulin Fab FragmentsIodine RadioisotopesRadiopharmaceuticalsTissue DistributionB7-H1 AntigenImmunoglobulin Fab FragmentsIodine-124Iodine RadioisotopesRadiopharmaceuticalsF(ab')2 fragmentI-124PD-L1PET imagingSHPP

Identifiers

PMID36759371

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.