Evidence map›Paper›PMID 36759316›Full record

ArticleMusculoskeletal science & practice2023

Self-reported physical function is strongly related to pain behavior and pain interference and weakly related to physical capacity in people with chronic low back pain.

Nicholas V Karayannis, Matthew Smuck, Christine Law, Sean C Mackey, James J Gross, Beth D Darnall, Julia Hush

Open access · greenAbstract read
In one paragraph

Article in Musculoskeletal science & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Using a measurement type-independent metric to compare patterns of determinants between patient-reported versus performance-based physical function in hemodialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nicholas V KarayannisOhio University, Athens, USA. Electronic address: nvkaray@ohio.edu.
Matthew SmuckStanford University, Palo Alto, USA. Electronic address: msmuck@stanford.edu.
Christine LawStanford University, Palo Alto, USA. Electronic address: cslaw@stanford.edu.
Sean C MackeyStanford University, Palo Alto, USA. Electronic address: smackey@stanford.edu.
James J GrossStanford University, Palo Alto, USA. Electronic address: gross@stanford.edu.
Beth D DarnallStanford University, Palo Alto, USA. Electronic address: bdarnall@stanford.edu.
Julia HushMacQuarie University, Sydney, Australia. Electronic address: julia.hush@mq.edu.au.
Palo Alto University · USMacquarie University · AUOhio University · US

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Stanford CAM Center for Chronic Back PainP01AT006651 · NCCIH · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2011 to 2018
$8.2M
Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
Neuroimaging and Mentoring in Translational Pain ResearchK24DA029262 · NIDA · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2010 to 2019
$1.9M
Research and Mentoring in Innovative Patient Oriented Pain and Opioid ScienceK24DA053564 · NIDA · STANFORD UNIVERSITY · PI Beth Denise Darnall · 2021 to 2026
$1.0M
Mentoring in Discovery and Validation of Clinical Chronic Pain BiomarkersK24NS126781 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2021 to 2021
$324k
NCATS NIH HHS UL1 TR003142NCCIH NIH HHS P01 AT006651NIDA NIH HHS DA053564-01NIDA NIH HHS K24 DA029262NIDA NIH HHS K24 DA053564NIDA NIH HHS T32 DA035165NINDS NIH HHS K24 NS126781
6 · The paper itself

Abstract

backgroundInclusion of self-reported and capacity-based measures may help to further elucidate the interactive link between how people think and move.

objectiveTo characterize the relationship between self-reported factors of physical function and pain with objective physical capacity measures.

designCross-sectional study of 328 adults with chronic low back pain (CLBP).

methodSpearman correlations assessed the relationship between pairs of measures. Multiple linear regression models assessed the association between self-reported measures of physical function and the grouping of physical capacity measures. Self-reported measures included Roland Morris Disability Questionnaire (RMDQ), PROMIS Physical Function, Pain Behavior, and Pain Interference; Fear-Avoidance Beliefs Questionnaire (FABQ), Pain Catastrophizing Scale (PCS), and Chronic Pain Acceptance Questionnaire (CPAQ). Capacity measures included walking speed and endurance, lower extremity functional strength, lumbopelvic range of motion, and trunk endurance.

resultsPROMIS Physical Function was directly and weakly correlated with walking speed (ρ = 0.26, 2-min walk) and inversely and weakly correlated with lower extremity strength (ρ = -0.29, 5x sit-to-stand). RMDQ was not correlated with any of the capacity-based measures. PROMIS Physical Function was inversely and moderately correlated with Pain Interference (ρ = -0.48) and Pain Behavior (ρ = -0.43), PCS (ρ = -0.36), and FABQ (ρ = -0.31). The RMDQ was strongly correlated with PROMIS Physical Function (ρ = -0.56), Pain Behavior (ρ = 0.51) and Pain Interference (ρ = 0.49); and moderately correlated with PCS (ρ = 0.37) and FABQ (ρ = 0.33). PROMIS Physical Function and RMDQ were not correlated with CPAQ. Lower scores on PROMIS Physical Function were weakly associated with lower measures of lower extremity strength (-0.30, 95% CI: -0.51 to -0.09, p = 0.005). Higher scores on RMDQ were also weakly associated with lower measures of lower extremity strength (0.26, 95% CI: 0.11 to 0.41, p = 0.001).

conclusionsA strong association emerged between self-reported limitations in physical function, pain behavior, and pain interference. A weak association emerged between self-reported physical function and lower extremity strength.

Indexed as

Low Back PainAdultCross-Sectional StudiesFearHumansSelf ReportSurveys and QuestionnairesPain behaviorPain interferencePhysical capacityPhysical function

Identifiers

PMID36759316
PMCPMC10566747
OpenAlexW4317757032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.