Evidence map›Paper›PMID 36759257›Full record

SynthesisBiological psychiatry2023

Machine Learning and Prediction in Fetal, Infant, and Toddler Neuroimaging: A Review and Primer.

Dustin Scheinost, Angeliki Pollatou, Alexander J Dufford, Rongtao Jiang, Michael C Farruggia, Matthew Rosenblatt, Hannah Peterson, Raimundo X Rodriguez, Javid Dadashkarimi, Qinghao Liang and 12 more

Abstract readSystematic Review
In one paragraph

Synthesis in Biological psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Deep learning in fetal, infant, and toddler neuroimaging research.Developmental cognitive neuroscience · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Brain-phenotype predictions can survive across diverse real-world data.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Dustin ScheinostDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Department of Biomedical Engineering, Yale University, New Haven, Connecticut; Department of Statistics and Data Science, Yale University, New Haven, Connecticut; Child Study Center, Yale School of Medicine, New Haven, Connecticut; Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut. Electronic address: dustin.scheinost@yale.edu.
Angeliki PollatouDepartment of Psychiatry, Columbia University Irving Medical Center, New York, New York.
Alexander J DuffordDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Rongtao JiangDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Michael C FarruggiaInterdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Matthew RosenblattDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut.
Hannah PetersonDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Raimundo X RodriguezInterdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Javid DadashkarimiDepartment of Computer Science, Yale University, New Haven, Connecticut.
Qinghao LiangDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut.
Wei DaiDepartment of Biostatistics, Yale School of Public Health, New Haven, Connecticut.
Maya L FosterDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut.
Chris C CampInterdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Link TejavibulyaInterdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Brendan D AdkinsonInterdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Huili SunDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut.
Jean YeInterdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Qi ChengDepartments of Neuroscience and Psychology, Smith College, Northampton, Massachusetts.
Marisa N SpannDepartment of Psychiatry, Columbia University Irving Medical Center, New York, New York.
Max RolisonChild Study Center, Yale School of Medicine, New Haven, Connecticut.
Stephanie NobleDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Margaret L WestwaterDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Interdepartmental Neuroscience Program (INP)T32NS041228 · NINDS · YALE UNIVERSITY · PI Charles A Greer, Marina R Picciotto · 2001 to 2026
$12.0M
NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Neuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7M
Establishing Early Brain Signatures associated with Maternal Immune Activation ExposureR01MH126133 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Dustin Scheinost, Marisa N Spann · 2022 to 2026
$4.2M
Training Program in Molecular MedicineT32GM100884 · NIGMS · YALE UNIVERSITY · PI LISTER, GEORGE, NITABACH, MICHAEL · 2013 to 2022
$1.8M
Midcareer investigator award in patient-oriented research in the area of perinatal-developmental neuroscienceK24MH127381 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPANN, MARISA N · 2021 to 2025
$804k
Constrained Network-Based Multiple Comparison CorrectionK00MH122372 · NIMH · YALE UNIVERSITY · PI NOBLE, STEPHANIE MARIE · 2019 to 2021
$242k
Empirical Power Analysis Tool for fMRIK99MH130894 · NIMH · YALE UNIVERSITY · PI NOBLE, STEPHANIE MARIE · 2022 to 2022
$123k
NCATS NIH HHS TL1 TR001864NCATS NIH HHS UL1 TR001863NIDA NIH HHS T32 DA022975NIGMS NIH HHS T32 GM100884NIMH NIH HHS K00 MH122372NIMH NIH HHS K24 MH127381NIMH NIH HHS K99 MH130894NIMH NIH HHS R01 MH126133NINDS NIH HHS T32 NS041228
6 · The paper itself

Abstract

Predictive models in neuroimaging are increasingly designed with the intent to improve risk stratification and support interventional efforts in psychiatry. Many of these models have been developed in samples of children school-aged or older. Nevertheless, despite growing evidence that altered brain maturation during the fetal, infant, and toddler (FIT) period modulates risk for poor mental health outcomes in childhood, these models are rarely implemented in FIT samples. Applications of predictive modeling in children of these ages provide an opportunity to develop powerful tools for improved characterization of the neural mechanisms underlying development. To facilitate the broader use of predictive models in FIT neuroimaging, we present a brief primer and systematic review on the methods used in current predictive modeling FIT studies. Reflecting on current practices in more than 100 studies conducted over the past decade, we provide an overview of topics, modalities, and methods commonly used in the field and under-researched areas. We then outline ethical and future considerations for neuroimaging researchers interested in predicting health outcomes in early life, including researchers who may be relatively new to either advanced machine learning methods or using FIT data. Altogether, the last decade of FIT research in machine learning has provided a foundation for accelerating the prediction of early-life trajectories across the full spectrum of illness and health.

Indexed as

Machine LearningNeuroimagingChildChild, PreschoolHumansInfantDeep learningElectroencephalogyFunctional magnetic resonance imagingFunctional near-infrared spectroscopyMagnetoencephalographyNeonates

Identifiers

PMID36759257
PMCPMC10259670

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.