Evidence map›Paper›PMID 36758858›Full record

ReviewAdvanced drug delivery reviews2023

Colonizing microbiota is associated with clinical outcomes in diabetic wound healing.

Gaofeng Wang, Zhen Lin, Yue Li, Lu Chen, Sashank K Reddy, Zhiqi Hu, L A Garza

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced drug delivery reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Nanozymes-Armed ProbioticResearch (Washington, D.C.) · 2026
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gaofeng WangDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510515, China; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21210, USA. Electronic address: wanggaofeng@smu.edu.cn.
Zhen LinDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Yue LiDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Lu ChenDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Sashank K ReddyDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21210, USA; Department of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Zhiqi HuDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong Province 510515, China.
L A GarzaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21210, USA; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21210, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21210, USA. Electronic address: LAG@jhmi.edu.

Funding

Retinoic acid synthesis induced by noncoding dsRNA controls RegenerationR01AR074846 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2019 to 2023
$2.3M
Injection of autologous volar fibroblasts to the stump site to allow pressure adaptation and enhanced prosthetic use in amputeesUG3AR079376 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2021 to 2021
$532k
NIAMS NIH HHS R01 AR074846NIAMS NIH HHS UG3 AR079376
6 · The paper itself

Abstract

With the development of society and the improvement of life quality, more than 500 million people are affected by diabetes. More than 10 % of people with diabetes will suffer from diabetic wounds, and 80 % of diabetic wounds will reoccur, so the development of new diabetic wound treatments is of great importance. The development of skin microbe research technology has gradually drawn people's attention to the complex relationship between microbes and diabetic wounds. Many studies have shown that skin microbes are associated with the outcome of diabetic wounds and can even be used as one of the indicators of wound prognosis. Skin microbes have also been found to have the potential to treat diabetic wounds. The wound colonization of different bacteria can exert opposing therapeutic effects. It is necessary to fully understand the skin microbes in diabetic wounds, which can provide valuable guidance for clinical diabetic wound treatment.

Indexed as

Diabetes MellitusMicrobiotaHumansPrognosisSkinWound HealingColonizing microbiotaDiabetic woundWound microenvironment

Identifiers

PMID36758858
PMCPMC10163681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.