Evidence map›Paper›PMID 36758660›Full record

ArticleSeminars in thoracic and cardiovascular surgery2024

Outcomes of Reoperative Aortic Root Replacement After Previous Acute Type A Dissection Repair.

Albert J Pedroza, Alex R Dalal, Aravind Krishnan, Nobu Yokoyama, Ken Nakamura, Emily Tognozzi, Y Joseph Woo, John W Macarthur, Michael P Fischbein

Open access · hybridAbstract read
In one paragraph

Article in Seminars in thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Albert J PedrozaDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Alex R DalalDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Aravind KrishnanDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Nobu YokoyamaDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Ken NakamuraDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Emily TognozziDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Y Joseph WooDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
John W MacarthurDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.
Michael P FischbeinDepartment of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford California.. Electronic address: mfischbe@stanford.edu.
Stanford University · USStanford Medicine · US

Funding

Marfan Aortic Embryologic Origin Influences Aneurysm FormationR01HL157949 · NHLBI · STANFORD UNIVERSITY · PI FISCHBEIN, MICHAEL PETER · 2022 to 2025
$2.6M
Stanford Integrated Cardiovascular/Pulmonary Residency Research Training ProgramR38HL143615 · NHLBI · STANFORD UNIVERSITY · PI Michael Peter Fischbein, Marlene Rabinovitch · 2020 to 2026
$2.2M
Developmental basis for vascular smooth muscle cell dysfunction in Marfan syndrome aortic aneurysmF32HL154681 · NHLBI · STANFORD UNIVERSITY · PI PEDROZA, ALBERT J. · 2020 to 2021
$137k
Extracellular Matrix Biomechanical Properties Contribute to Aneurysm Formation in Marfan SyndromeF32HL160058 · NHLBI · STANFORD UNIVERSITY · PI DALAL, ALEX R. · 2021 to 2022
$134k
NHLBI NIH HHS F32 HL154681NHLBI NIH HHS F32 HL160058NHLBI NIH HHS R01 HL157949NHLBI NIH HHS R38 HL143615
6 · The paper itself

Abstract

Limited aortic root repair for acute type A dissection is associated with greater risk of proximal reoperations compared to full aortic root replacement. Surgical outcomes for patients undergoing reoperative root replacement after previous dissection repair are unknown. This study seeks to determine outcomes for these patients to further inform the debate surrounding optimal upfront management of the aortic root in acute dissection. Retrospective record review of all patients who underwent full aortic root replacement after a previous type A dissection repair operation at a tertiary academic referral center from 2004-2020 was performed. Among 57 cases of reoperative root replacement after type A repair, 35 cases included concomitant aortic arch replacements, and 21 cases involved coronary reconstruction (unilateral or bilateral modified Cabrol grafts). There were 3 acute postoperative strokes and 4 operative mortalities (composite 30-day and in-hospital deaths, 7.0%). Mid-term outcomes were equivalent for patients who required arch replacement compared to isolated proximal repairs (81.8% vs 80.6% estimated 5-year survival, median follow-up 5.53 years. Reoperative root replacement after index type A dissection repairs, including those with concomitant aortic arch replacement and/or coronary reconstruction is achievable with acceptable outcomes at an experienced aortic center.

Indexed as

Aortic DissectionBlood Vessel Prosthesis ImplantationReoperationAcute DiseaseAgedAortic AneurysmFemaleHospital MortalityHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsAortic dissectionAortic root replacementOutcomesreoperation

Identifiers

PMID36758660
PMCPMC12276899
OpenAlexW4319455811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.