Evidence map›Paper›PMID 36757961›Full record

ArticleExperimental and clinical psychopharmacology2023

A preliminary investigation of salivary α-amylase as a novel biomarker of subjective response to alcohol: A brief report.

Scott E King, Jack T Waddell, William R Corbin

Open access · hybridAbstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Scott E KingDepartment of Psychology, Arizona State University.ORCID 0000-0002-0868-0149
Jack T WaddellDepartment of Psychology, Arizona State University.
William R CorbinDepartment of Psychology, Arizona State University.
Arizona State University · US

Funding

Contextual Influences on Alcohol Response and its Relation to Drinking OutcomesR01AA021148 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CORBIN, WILLIAM R · 2013 to 2017
$1.5M
NIAAA NIH HHSNIAAA NIH HHS R01 AA021148
6 · The paper itself

Abstract

Alcohol misuse represents a universal public health concern that spans multiple demographics. As such, understanding shared, biological indicators of alcohol-related risk is vital to implementing targeted prevention and intervention efforts. Self-report measures of subjective response to alcohol (SR) capture both psychological and pharmacological effects of alcohol and robustly predict patterns of alcohol use, negative consequences, and the development of alcohol use disorders. Importantly, several biological markers of alcohol's sedating effects, including cortisol, have been identified and complement subjective response assessments. However, biological markers of alcohol's stimulating effects are less understood. Studies have implicated alcohol-induced changes in heart rate as a viable marker, but heart rate measurements are susceptible to measurement error. Salivary α-amylase, a reliable indicator of sympathetic nervous system activation, represents a promising alternative biomarker of alcohol-induced stimulation. Using data from a large, placebo-controlled alcohol administration study (

Indexed as

AlcoholismSalivary alpha-AmylasesAlcohol DrinkingBiomarkersEthanolHumansBiomarkersEthanolSalivary alpha-Amylases

Identifiers

PMID36757961
PMCPMC10409871
OpenAlexW4319655791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.