Evidence map›Paper›PMID 36757808›Full record

ArticleAngewandte Chemie (International ed. in English)2023

Directed Evolution of an Iron(II)- and α-Ketoglutarate-Dependent Dioxygenase for Site-Selective Azidation of Unactivated Aliphatic C-H Bonds.

Christian A Gomez, Dibyendu Mondal, Qian Du, Natalie Chan, Jared C Lewis

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

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  12. Enantioconvergent benzylic C(spScience (New York, N.Y.) · 2025
    Article
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  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christian A GomezDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA.
Dibyendu MondalDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA.
Qian DuDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA.
Natalie ChanDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA.
Jared C LewisDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0003-2800-8330
Indiana University Bloomington · USKalamazoo Public Library · US

Funding

Directed Evolution of Halogenases For Small Molecule FunctionalizationR01GM115665 · NIGMS · UNIVERSITY OF CHICAGO · PI LEWIS, JARED C · 2015 to 2022
$2.5M
NIGMS NIH HHS R01 GM115665
6 · The paper itself

Abstract

Fe

Indexed as

Alpha-Ketoglutarate-Dependent Dioxygenase FTOIronAminesFerrous CompoundsOxygenasesAlpha-Ketoglutarate-Dependent Dioxygenase FTOAminesFerrous CompoundsIronOxygenasesAzidation, Non-Heme IronC−H FunctionalizationDirected EvolutionKetoglutarate

Identifiers

PMID36757808
PMCPMC10050089
OpenAlexW4319655569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.