Evidence map›Paper›PMID 36757624›Full record

ArticleJournal of experimental orthopaedics2023

Free-floating medial meniscus implant kinematics do not change after simulation of medial open-wedge high tibial osteotomy and notchplasty.

Matthias Sukopp, Maoz Shemesh, Elena Pruech, Eran Linder-Ganz, Scott Hacker, Vincenzo Condello, Jonas Schwer, Anita Ignatius, Lutz Dürselen, Andreas Martin Seitz

Open access · goldAbstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The Current State of Meniscus Replacements.Current reviews in musculoskeletal medicine · 2024
    Review
  4. Shaping experimental orthopaedics.Journal of experimental orthopaedics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Matthias SukoppInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, Ulm University, Medical Center, Helmholtzstrasse 14, 89081, Ulm, Germany.
Maoz ShemeshActive Implants LLC, 6060 Primacy Parkway, Suite 460, Memphis, TN, USA.
Elena PruechActive Implants LLC, 6060 Primacy Parkway, Suite 460, Memphis, TN, USA.
Eran Linder-GanzActive Implants LLC, 6060 Primacy Parkway, Suite 460, Memphis, TN, USA.
Scott HackerGrossmont Orthopedic Medical Group, 5565 Grossmont Center Drive, Building 3, Suite 256, La Mesa, CA, USA.
Vincenzo CondelloHumanitas Castelli Clinic, Via Mazzini, 11, Bergamo, Italy.
Jonas SchwerInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, Ulm University, Medical Center, Helmholtzstrasse 14, 89081, Ulm, Germany.
Anita IgnatiusInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, Ulm University, Medical Center, Helmholtzstrasse 14, 89081, Ulm, Germany.
Lutz DürselenInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, Ulm University, Medical Center, Helmholtzstrasse 14, 89081, Ulm, Germany.
Andreas Martin SeitzInstitute of Orthopedic Research and Biomechanics, Center of Trauma Research Ulm, Ulm University, Medical Center, Helmholtzstrasse 14, 89081, Ulm, Germany. andreas.seitz@uni-ulm.de.ORCID http://orcid.org/0000-0001-8174-8552
Helmholtz-Institute Ulm · DEActive Implants (United States) · USHumanitas Castelli · ITSharp Grossmont Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this in-vitro study was to examine the kinematics of an artificial, free-floating medial meniscus replacement device under dynamic loading situations and different knee joint states.

methodsA dynamic knee simulator was used to perform dynamic loading exercises on three neutrally aligned and three 10° valgus aligned (simulating a medial openwedge high tibial osteotomy - MOWHTO) left human cadaveric knee joints. The knee joints were tested in three states (intact, conventional notchplasty, extended notchplasty) while 11 randomised exercises were simulated (jump landing, squatting, tibial rotation and axial ground impacts at 10°, 30° and 60° knee joint flexion) to investigate the knee joint and implant kinematics by means of rigidly attached reflective marker sets and an according motion analysis.

resultsThe maximum implant translation relative to the tibial plateau was < 13 mm and the maximum implant rotation was < 19° for all exercises. Both, the notchplasties and the valgus knee alignment did not affect the device kinematics.

conclusionsThe results of the present in-vitro study showed that the non-anchored free-floating device remains within the medial knee joint gap under challenging dynamic loading situations without indicating any luxation tendencies. This also provides initial benchtop evidence that the device offers suitable stability and kinematic behaviour to be considered a potential alternative to meniscus allograft transplantation in combination with an MOWHTO, potentially expanding the patient collective in the future.

Identifiers

PMID36757624
PMCPMC9911568
OpenAlexW4319657091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.