Evidence map›Paper›PMID 36757620›Full record

ArticleJournal of cancer research and clinical oncology2023

Prevalence and severity of anxiety in cancer patients: results from a multi-center cohort study in Germany.

Ute Goerling, Andreas Hinz, Uwe Koch-Gromus, Julia Marie Hufeld, Peter Esser, Anja Mehnert-Theuerkauf

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Intensive nursing interventions for post-treatment anxiety and depression in bladder cancer: A systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Beyond image quality: Patient experience with long-axial field-of-view and standard PET/CT systems.European journal of nuclear medicine and molecular imaging · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ute GoerlingCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charité Comprehensive Cancer Center, Charitéplatz 1, 10117, Berlin, Germany. ute.goerling@charite.de.ORCID http://orcid.org/0000-0001-8157-3836
Andreas HinzDepartment of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Leipzig, Germany.
Uwe Koch-GromusDepartment of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Julia Marie HufeldDepartment of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Leipzig, Germany.
Peter EsserDepartment of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Leipzig, Germany.
Anja Mehnert-TheuerkaufDepartment of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Leipzig, Germany.
Leipzig University · DEHumboldt-Universität zu Berlin · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnxiety is an accompanying symptom in cancer patients that can have a negative impact on patients. The aim of the present analyses is to determine the prevalence of anxiety, taking into account sociodemographic and medical variables, and to determine the odds ratio for the occurrence of anxiety in cancer patients compared to general population.

methodsIn this secondary analyses, we included 4,020 adult cancer patients during and after treatment from a multi-center epidemiological study from 5 regions in Germany in different treatment settings and a comparison group consisting of 10,000 people from the general population in Germany. Anxiety was measured with the Generalized Anxiety Disorder (GAD-7) questionnaire. In multivariate analyses adjusted for age and sex, we calculated the odds of being anxious.

resultsThe prevalence of anxiety was observed to be 13.8% (GAD-7 ≥ 10). The level of anxiety was significant higher for patients in rehabilitation, compared to patients during inpatient and outpatient treatment (p = .013). Comparison with the general population yielded a 2.7-fold increased risk for anxiety among cancer patients (95% CI 2.4-3.1; p < .001). Patients with bladder cancer (OR, 5.3; 95% CI 3.0-9.4) and testicular cancer (OR, 5.0; 95% CI 2.1-12.1) showed the highest risk of having high levels of anxiety.

conclusionThe results highlight the importance of identifying anxiety in cancer patients.

Indexed as

Testicular NeoplasmsAdultAnxietyAnxiety DisordersCohort StudiesGermanyHumansMalePrevalenceAnxietyAnxiety symptomsCancerGAD-7Oncology

Identifiers

PMID36757620
PMCPMC10356888
OpenAlexW4319655911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.