Evidence map›Paper›PMID 36757494›Full record

ArticleEuropean journal of pediatrics2023

Comparison of lung ultrasound scores with clinical models for predicting bronchopulmonary dysplasia.

Zhenyu Li, Xin Mu, Dan Dang, Xiaoming Lv, Shuyu Si, Yiyi Guo, Hui Wu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Observational
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhenyu LiDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China.
Xin MuDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China.
Dan DangDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China.
Xiaoming LvDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China.
Shuyu SiDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China.
Yiyi GuoDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China.
Hui WuDepartment of Neonatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China. wuhui@jlu.edu.cn.ORCID http://orcid.org/0000-0002-7649-4575
Jilin University · CN

Funding

Scientific Research Foundation of the Department of Science and Technology of Jilin Province, China 20190701050GH
6 · The paper itself

Abstract

Lung ultrasound scores (LUSs) have been demonstrated to accurately predict moderate-to-severe bronchopulmonary dysplasia (msBPD). This study attempted to explore the additional value of LUSs for predicting msBPD compared to clinical multivariate models in different gestational age (GA) groups. The study prospectively recruited preterm infants with GA < 32 weeks. Lung ultrasound was performed on days 3, 7, 14, and 21 after birth. A linear mixed-effects regression model was used to evaluate LUS evolution in infants born before and after 28 weeks. The receiver operating characteristic (ROC) procedure was used to analyze the reliability of LUS and clinical multivariable models for predicting msBPD. The optimal time to predict msBPD in all infants was 7 days with a cut-off point of 5 (area under the ROC (AUROC) curve: 0.78, 95% confidence interval (CI): 0.71-0.84). In infants with GA ≥ 28 weeks, LUSs provided a moderate diagnostic accuracy for all four time points (AUROC curve: 0.74-0.78), and the AUROC curve for the clinical multivariable model on day 14 was 0.91 (95% CI: 0.84-0.96), which was significantly higher than that of LUSs (AUROC curve: 0.77, 95% CI: 0.68-0.85, P < 0.05). In infants born at 23-27 weeks, LUSs showed a low diagnostic accuracy with higher cut-off points to predict msBPD, and the AUROC curve for GA to predict msBPD was 0.75 (95% CI: 0.59-0.85), providing diagnostic accuracy similar to that of LUSs.  Conclusion: The contribution of LUSs to predict msBPD in infants with different GAs remains controversial and requires further investigation. What is Known: • Lung ultrasound scores (LUSs) have been demonstrated to accurately predict moderate-to-severe bronchopulmonary dysplasia in infants with gestational age (GA)＜32 weeks. What is New: • The LUSs evolution differed between extremely preterm infants born before 28 weeks and preterm infants born at 28-32 weeks of gestation. • LUSs provided similar moderate predictive performance as GA-adjusted LUS and clinical multivariate models in infants born after 28 weeks, while LUSs seem to be less helpful in infants born before 28 weeks.

Indexed as

Bronchopulmonary DysplasiaGestational AgeHumansInfantInfant, Extremely PrematureInfant, NewbornLungReproducibility of ResultsBronchopulmonary dysplasia (BPD)Gestational age (GA)Lung ultrasound score (LUS)Prediction

Identifiers

PMID36757494
PMCPMC10167145
OpenAlexW4319655991

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.