Evidence map›Paper›PMID 36757468›Full record

ArticleWorld journal of urology2023

The effect of irrigation rate on intrarenal pressure in an ex vivo porcine kidney model-preliminary study with different flexible ureteroscopes and ureteral access sheaths.

Wenfeng Guan, Jian Liang, Dong Wang, Hansheng Lin, Shaotong Xie, Shangjin Chen, Jingwei He, Abai Xu

Abstract read
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In one paragraph

Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wenfeng Guan *Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Jian Liang *Department of Urology, The Affiliated Yangjiang People's Hospital of Guangdong Medical University, Yangjiang, Guangdong, China.
Dong WangDepartment of Urology, The People's Hospital of Huantai, Zibo City, Shandong, China.
Hansheng LinDepartment of Urology, The Affiliated Yangjiang People's Hospital of Guangdong Medical University, Yangjiang, Guangdong, China.
Shaotong XieDepartment of Urology, The Affiliated Yangjiang People's Hospital of Guangdong Medical University, Yangjiang, Guangdong, China.
Shangjin ChenDepartment of Urology, The Affiliated Yangjiang People's Hospital of Guangdong Medical University, Yangjiang, Guangdong, China.
Jingwei HeDepartment of Urology, The Affiliated Yangjiang People's Hospital of Guangdong Medical University, Yangjiang, Guangdong, China. 18900808800@163.com.
Abai XuDepartment of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China. lc96xab@163.com.ORCID http://orcid.org/0000-0001-5204-6965
Guangdong Medical College · CNXintai People's Hospital · CNZhujiang Hospital · CN

Funding

the Mobility Programme of National Natural Science Foundation of China Grant NO.M-0299
6 · The paper itself

Abstract

introductionUreteral access sheath (UAS) and irrigation are used in flexible ureteroscopy (fURS). Both conventional UAS (cUAS) and vacuum-assisted UAS (vaUAS) are currently available. Irrigation increases the intrarenal pressure (IRP). Our objectives were to study the effects of various irrigation rates on IRP using different sizes of fURS in different sizes and functions of UAS. MATERIALS AND

methodsTen freshly harvested porcine kidneys served as the study subjects. 11/13F and 12/14F cUAS and vaUAS with 2.8 mm and 3.2 mm fURS were experimented on in various scope/sheath combinations. 6F pressure monitor catheters were placed into upper, middle, and lower calyces. IRPs were recorded under different irrigation rates in cUAS and vaUAS, with either 150 or 300 mmHg aspiration pressures, and with air vent either open or closed.

results12/14F cUAS with 2.8 mm fURS could maintain IRPs below 35 mmHg with irrigation rates up to 200 cc/min. With 3.2 mm fURS, the rate dropped to 110-120 cc/min. With 12/14F vaUAS and vent closed, the IRP remained less than 5 mmHg at 200 cc/min irrigation for both fURS. For 11/13F cUAS, the < 35 mmHg threshold for 2.8 mm fURS was 80-90 cc/min; for 3.2 mm fURS, it was 30-40 cc/min. For 11/13F vaUAS with vent closed, IRPs remained < 5 mmHg at 200 cc/min irrigation for both scopes.

conclusionBoth 12F cUAS and vaUAS can be used safely with 2.8 mm fURS up to 200 cc/min irrigation. With either a smaller sheath or a larger scope, vaUAS with vent closed can maintain IRP in a safe range up 200 cc/min irrigation. vaUAS with vent open performed marginally better than cUAS.

Indexed as

Kidney CalculiUreteroscopesAnimalsKidneyPressureSwineTherapeutic IrrigationUreteroscopyIntrarenal pressurePorcine kidneyUreteral access sheath

Identifiers

PMID36757468
OpenAlexW4319655521

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.