ArticleAmerican journal of epidemiology2023
Direct Effect of Life-Course Socioeconomic Status on Late-Life Cognition and Cognitive Decline in the Rush Memory and Aging Project.
Article in American journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of the association between life-course socioeconomic status and late-life cognitive decline.Journal of epidemiology and community health · 2026Pooled it
- Effect of a cash transfer intervention on memory decline and dementia probability in older adults in rural South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2024Trial
- Income dynamics and risk of early-onset dementia: a nationwide cohort study.Alzheimer's research & therapy · 2026Article
- The Brain Vulnerability Index: Development and Validation of a Machine Learning-Derived, Community-Informed Geospatial Risk Score for Cognitive Impairment.Research square · 2026Article
- The role of life-course socioeconomic position in cognitive change and mild cognitive impairment among middle-aged and older US Hispanic/Latinos.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Associations of Lifetime Cognitive Enrichment With Incident Alzheimer Disease Dementia, Cognitive Aging, and Cognitive Resilience.Neurology · 2026Article
- Cumulative poverty across early adulthood and midlife cognition: findings from the national longitudinal survey of youth.Journal of epidemiology and community health · 2026Article
- Can Raising grandchildren prevent or slow cognitive decline in Chinese elderly?BMC public health · 2026Article
- Associations of life course social determinants of health, social mobility with cognitive function and roles of social participation and lifestyle: a multicohort study.BMC medicine · 2025Article
- Cognitive maintenance in older adults in social classes: a secondary analysis of the longitudinal SHARE data.Journal of epidemiology and community health · 2025Article
- Lifetime Socioeconomic Status, Cognitive Decline, and Brain Characteristics.JAMA network open · 2025Article
- Association of psychosocial state with subsequent risk of dementia: a prospective cohort study based on the UK Biobank.Alzheimer's research & therapy · 2024Article
- Investigating the individual and joint effects of socioeconomic status and lifestyle factors on mild cognitive impairment in older Italians living independently in the community: results from the NutBrain study.The journal of nutrition, health & aging · 2024Observational
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5 authors.
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Abstract
The role of socioeconomic status (SES) across the life course in late-life cognition is unclear. We tested the hypotheses that: 1) High SES in childhood, young adulthood, midlife, and late life have independent causal effects on higher cognition level and slower cognitive decline; 2) Compared with stable low SES (referent), stable high SES has the largest estimated effect for higher cognition level and slower decline among life-course SES combinations. The Rush Memory and Aging Project enrolled 1,940 dementia-free older adults in northeastern Illinois (1997-2018). We used inverse probability-weighted marginal structural models to estimate the joint and independent effect of each life-course SES on global and domain-specific cognition. A total of 1,746 participants had, on average, 6 years of follow-up. High SES at each life-course stage starting in young adulthood had a protective estimated effect on global and domain-specific cognition intercepts. Compared with consistently low SES, consistently high SES (β = 0.64, 95% confidence interval: 0.48, 0.93) and high SES beyond childhood (β = 0.64, 95% confidence interval: 0.47, 0.83) had the largest benefit for global cognition intercepts. None of the life-course SES measures influenced rate of global or domain-specific decline. Additional understanding of life-course SES components influencing cognitive level is warranted.
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