ArticlePlant physiology2023
Two interacting basic helix-loop-helix transcription factors control flowering time in rice.
Article in Plant physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Characterizing the molecular mechanism of the PmIDD5-PmbHLH130-PmCOL5 transcriptional cascade on flowering in Prunus mume.BMC plant biology · 2026Article
- An F-box protein OsFKF1 interacts with either OsGI or Hd1 and mediates the degradation of OsGI to control flowering time in rice.Science advances · 2026Article
- Comparative transcriptome analysis reveals key genes and regulatory networks regulating flowering in rice varieties with different photoperiod sensitivity.BMC plant biology · 2026Article
- An α/β-Hydrolase GmABHD6 Controls Seed Oil Content and Yield in Soybean.Plant biotechnology journal · 2026Article
- Genome-wide association study of a Guinea grass (Megathyrsus maximus) diversity panel reveals the genetic basis of agronomic and nutritional traits.BMC plant biology · 2025Article
- Genome-Wide Identification and Expression Analysis of theInternational journal of molecular sciences · 2025Article
- An auxin response factor regulates tiller angle and shoot gravitropism by directly activating related gene expression in rice.Journal of advanced research · 2025Article
- GmMEKK2 Disrupts the MKK1/2-MPK4 Cascade to Amplify Immune Signalling and Confer Enhanced Resistance to Soybean Mosaic Virus.Molecular plant pathology · 2025Article
- JMJ720 regulates flowering time in rice via H3K9 demethylation of Hd1.Plant biotechnology journal · 2025Article
- Identification of HSSP1 as a regulator of soybean protein content through QTL analysis and Soy-SPCC network.Plant biotechnology journal · 2025Article
- Exploring the multifaceted dynamics of flowering time regulation in field crops: Insight and intervention approaches.The plant genome · 2025Review
- Inactivation of GH3.5 by COP1-mediated K63-linked ubiquitination promotes seedling hypocotyl elongation.Nature communications · 2025Article
- A Series of Novel Alleles ofPlants (Basel, Switzerland) · 2025Article
- Genome-wide analysis of bHLH transcription factor family reveals their involvement in kernel development and biotic stress responses in Chinese chestnut.Frontiers in plant science · 2025Article
- Genome-Wide Identification and Role of theInternational journal of molecular sciences · 2024Article
- KIN10-mediated HB16 protein phosphorylation and self-association improve cassava disease resistance by transcriptional activation of lignin biosynthesis genes.Plant biotechnology journal · 2024Article
- Improving Rice Quality by Regulating the Heading Dates of Rice Varieties without Yield Penalties.Plants (Basel, Switzerland) · 2024Article
- Basic helix-loop-helix (bHLH) gene family in rye (Secale cereale L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses.BMC genomics · 2024Article
- Genome-wide identification of the bHLH gene family inFrontiers in plant science · 2024Article
- Unlocking Nature's Clock: CRISPR Technology in Flowering Time Engineering.Plants (Basel, Switzerland) · 2023Review
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Authors and funding
10 authors at 1 institution in 1 country.
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Abstract
Flowering time is one of the most important agronomic traits affecting the adaptation and yield of rice (Oryza sativa). Heading date 1 (Hd1) is a key factor in the photoperiodic control of flowering time. In this study, two basic helix-loop-helix (bHLH) transcription factors, Hd1 Binding Protein 1 (HBP1) and Partner of HBP1 (POH1) were identified as transcriptional regulators of Hd1. We generated knockout mutants of HBP1 and ectopically expressed transgenic lines of the two bHLH transcription factors and used these lines to investigate the roles of these two factors in regulating flowering time. HBP1 physically associated with POH1 forming homo- or heterodimers to perform their functions. Both HBP1 and POH1 bound directly to the cis-acting elements located in the promoter of Hd1 to activate its expression. CRISPR/Cas9-generated knockout mutations of HBP1, but not POH1 mutations, promoted earlier flowering time; conversely, HBP1 and POH1 overexpression delayed flowering time in rice under long-day and short-day conditions by activating the expression of Hd1 and suppressing the expression of Early heading date 1 (Ehd1), Heading date 3a (Hd3a), and Rice Flowering locus T 1 (RFT1), thus controlling flowering time in rice. Our findings revealed a mechanism for flowering time control through transcriptional regulation of Hd1 and laid theoretical and practical foundations for improving the growth period, adaptation, and yield of rice.
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