Evidence map›Paper›PMID 36756713›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2023

Risk of dementia associated with body mass index, changes in body weight and waist circumference in older people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study.

Bo-Jen Chen, Anniek J Sluiman, Wardah Khalid, Mark W J Strachan, Jackie F Price

Open access · hybridAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. The impact ofAlzheimer's & dementia (Amsterdam, Netherlands)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Bo-Jen ChenCollege of Medicine and Veterinary Medicine, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-7177-2775
Anniek J SluimanCollege of Medicine and Veterinary Medicine, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-3633-2643
Wardah KhalidCollege of Medicine and Veterinary Medicine, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-6527-4729
Mark W J StrachanMetabolic Unit, Western General Hospital, Edinburgh, UK.ORCID 0000-0003-2628-1202
Jackie F PriceCollege of Medicine and Veterinary Medicine, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-3251-3970
Edinburgh College · GBWestern General Hospital · GB

Funding

Chief Scientist Office CZQ/1/38Medical Research Council G0500877
6 · The paper itself

Abstract

aims/hypothesisTo determine the relationship of dementia with preceding body mass index (BMI), changes in body weight and waist circumference in older people with type 2 diabetes.

methodsIn the Edinburgh Type 2 Diabetes Study (1064 men and women with type 2 diabetes, aged 60-75), body weight, waist circumference and BMI were measured at baseline and after 4 years in a subgroup (n = 821). Percentage body weight and waist circumference change over 4 years were calculated. Data on incident dementia was recorded during a median follow-up time of 10.84 years. Survival models considering a range of co-variables and/or death as a competing risk were used to estimate the risks of dementia associated with each weight-related variable.

resultsA total of 105 incident dementia events were recorded. When compared with people in the lowest BMI group (<25 kg/m CONCLUSIONS/INTERPRETATIONS: Both a lower BMI and weight loss over a period of years are indicative of increased dementia risk for older people with type 2 diabetes, while waist circumference changes may be less informative.

Indexed as

Diabetes Mellitus, Type 2AgedBody Mass IndexBody WeightFemaleHumansMaleRisk FactorsWaist Circumferencebody mass index (BMI)body weight lossdementiatype 2 diabeteswaist circumference

Identifiers

PMID36756713
PMCPMC10947035
OpenAlexW4319655683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.