Evidence map›Paper›PMID 36756679›Full record

ArticleCNS neuroscience & therapeutics2023

The CaMKII-dependent phosphorylation of GABA

Ming F Lu, Qiang Fu, Tian Y Qiu, Jian H Yang, Qing H Peng, Zhen Z Hu

Open access · goldAbstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Agonizing GABAFrontiers in pharmacology · 2025
    Article
  3. Restoring GABAFrontiers in molecular neuroscience · 2024
    Article
  4. Article
  5. The CaMKII-dependent phosphorylation of GABACNS neuroscience & therapeutics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ming F LuDepartment of Pathophysiology, College of Basic Medicine, Nanchang University, Nanchang, Jiangxi, China.
Qiang FuDepartment of Respiration, Department Two, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi, China.
Tian Y QiuDepartment of Pathophysiology, College of Basic Medicine, Nanchang University, Nanchang, Jiangxi, China.
Jian H YangDepartment of Physiology, College of Basic Medicine, Nanchang University, Nanchang, Jiangxi, China.
Qing H PengDepartment of Anesthesiology, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, China.
Zhen Z HuDepartment of Pathophysiology, College of Basic Medicine, Nanchang University, Nanchang, Jiangxi, China.ORCID 0000-0001-7020-3071
Nanchang University · CNJiangxi Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have established that the regulation of prolonged, distal neuronal inhibition by the GABA

aimsHere, we show that GABA MATERIALS &

methodsBy immunofluorescent labeling, flow cytometry analysis, Co-immunoprecipitation and open field test, we measured the role of Ca

resultsRepeated cocaine treatment in rats (15 mg/kg) significantly decreases membrane levels of GABA

conclusionThese findings reveal a new mechanism by which pCaMKII-GABA

Indexed as

CocaineAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2gamma-Aminobutyric AcidNucleus AccumbensPhosphorylationRatsReceptors, GABA-BCalcium-Calmodulin-Dependent Protein Kinase Type 2Cocainegamma-Aminobutyric AcidReceptors, GABA-Bbehavioral sensitizationCaMKIIcocaineGABABRnucleus accumbensphosphorylation

Identifiers

PMID36756679
PMCPMC10068462
OpenAlexW4319656516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.