Evidence map›Paper›PMID 36756582›Full record

ArticleRSC advances2023

An electrochemical aptasensor based on AuNRs/AuNWs for sensitive detection of apolipoprotein A-1 (ApoA1) from human serum.

Raudhatul Husna, Chitra Padmakumari Kurup, Mohd Afaque Ansari, Noor Faizah Mohd-Naim, Minhaz Uddin Ahmed

Abstract read
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Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raudhatul HusnaBiosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam Jalan Tungku Link Gadong BE 1410 Brunei Darussalam minhaz.ahmed@ubd.edu.bn minhaz.ahmed@outlook.com.
Chitra Padmakumari KurupPAPRSB Institute of Health Sciences, Universiti Brunei Darussalam Jalan Tungku Link Gadong BE 1410 Brunei Darussalam.
Mohd Afaque AnsariBiosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam Jalan Tungku Link Gadong BE 1410 Brunei Darussalam minhaz.ahmed@ubd.edu.bn minhaz.ahmed@outlook.com.
Noor Faizah Mohd-NaimBiosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam Jalan Tungku Link Gadong BE 1410 Brunei Darussalam minhaz.ahmed@ubd.edu.bn minhaz.ahmed@outlook.com.
Minhaz Uddin AhmedBiosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam Jalan Tungku Link Gadong BE 1410 Brunei Darussalam minhaz.ahmed@ubd.edu.bn minhaz.ahmed@outlook.com.ORCID https://orcid.org/0000-0002-8267-8506

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For early detection and diagnosis of cancer, it is essential to develop an electrochemical biosensor that is quick, accurate, and sensitive. Here, we use gold nanorod (AuNR) and gold nanowire (AuNW) nanocomposites (AuNR/AuNW/CS) as electrode modifiers on a glassy carbon electrode (GCE) to construct a sensitive label-free electrochemical aptasensor to detect ApoA1. The thiolated ApoA1-specific aptamers were immobilized onto the modified electrode surface through self-assembled monolayers. Electrochemical techniques, such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV), were used to analyze the fabrication steps. The concentration of ApoA1 was measured with DPV on the aptasensor, with a linear range of 0.1 to 1000 pg mL

Identifiers

PMID36756582
PMCPMC9890643

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.