Evidence map›Paper›PMID 36756546›Full record

ArticleRSC advances2023

Liposomes loaded with dual clinical photosensitizers for enhanced photodynamic therapy of cervical cancer.

Gulinigaer Alimu, Ting Yan, Lijun Zhu, Zhong Du, Rong Ma, Huimin Fan, Shuang Chen, Nuernisha Alifu, Xueliang Zhang

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Chlorin Activity Enhancers for Photodynamic Therapy.Molecules (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Gulinigaer AlimuDepartment of Epidemiology and Health Statistics, School of Public Health, Xinjiang Medical University Urumqi 830054 China shuxue2456@126.com nens_xjmu@126.com.
Ting YanDepartment of Epidemiology and Health Statistics, School of Public Health, Xinjiang Medical University Urumqi 830054 China shuxue2456@126.com nens_xjmu@126.com.
Lijun ZhuState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, School of Medical Engineering and Technology, Xinjiang Medical University Urumqi 830054 China.
Zhong DuDepartment of Gynecology, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830054 China.
Rong MaDepartment of Gynecology, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830054 China.
Huimin FanState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, School of Medical Engineering and Technology, Xinjiang Medical University Urumqi 830054 China.
Shuang ChenDepartment of Gynecology, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830054 China.
Nuernisha AlifuDepartment of Epidemiology and Health Statistics, School of Public Health, Xinjiang Medical University Urumqi 830054 China shuxue2456@126.com nens_xjmu@126.com.ORCID https://orcid.org/0000-0003-2466-4592
Xueliang ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Xinjiang Medical University Urumqi 830054 China shuxue2456@126.com nens_xjmu@126.com.
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) has become a potential anti-cancer strategy owing to its negligible invasiveness, low toxicity, and high selectivity. The photosensitizer (PS) plays an indispensable role in PDT. Herein, a novel type of PS (Ce6-MB@Lips) which can be excited by a near-infrared (NIR) laser was designed and synthesized. Methylene blue (MB) and Chlorin e6 (Ce6), two organic dyes approved by the Food and Drug Administration (FDA), were used to prepare Ce6-MB@Lips by thin-film dispersion method, which improve the water solubility of Ce6 and reduce the cytotoxicity of MB. The Ce6-MB@Lips were shown to have a spherical nanostructure with an average particle size of 160.3 nm and excellent water solubility. Then the optical properties of Ce6-MB@Lips were further studied. Ce6-MB@Lips showed absorption peaks at 413 nm/670 nm and fluorescence peak at 697 nm. Compared with Ce6@Lips and MB@Lips, Ce6-MB@Lips showed better stability, stronger fluorescence intensity, and higher singlet oxygen (

Identifiers

PMID36756546
PMCPMC9872094
OpenAlexW4319657194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.