ArticleKidney diseases (Basel, Switzerland)2023
Trends of Urolithiasis in China: A National Study Based on Hospitalized Patients from 2013 to 2018.
Article in Kidney diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 32 citations in OpenAlex.
- SIRT1 regulates CaOx crystal-induced exacerbation of renal mitochondrial dysfunction and fibrosis through PPAR-α in aged mice.Journal of molecular medicine (Berlin, Germany) · 2026Article
- Development of a machine learning model for predicting urosepsis after ureteroscopic lithotripsy.Urolithiasis · 2026Article
- Article
- Adherence to the Dietary Index for Gut Microbiota and reduced risk of nephrolithiasis: a case-control study of Chinese adults.Frontiers in nutrition · 2026Article
- Applying urinary ultrasound combined with CT to predict the risk of spontaneous ureteral stone passage.BMC urology · 2025Article
- Investigating the pathogenesis of urolithiasis through gut microbiome, plasma metabolome and inflammatory proteome: a mediation Mendelian randomization study.Clinical epigenetics · 2025Article
- Higher Life's Essential 8 score is associated with lower risk of kidney stones in Chinese adults: a cross-sectional study.BMC public health · 2025Article
- Linoelaidic acid alleviates COM-induced kidney injury and crystal deposition via the PPARγ/MAPK signaling pathway.Urolithiasis · 2025Article
- [Surgical techniques and clinical outcomes of upper urinary tract reconstruction for stone-related ureteral strictures].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Observational
- Drug-induced kidney stones: a real-world pharmacovigilance study using the FDA adverse event reporting system database.Frontiers in pharmacology · 2025Article
- Comprehensive biomarker profiling reveals distinct molecular signatures across stone types: a large-scale cross-sectional study in Southern China.Frontiers in physiology · 2025Article
- Association Between the CALLY Index and Kidney Stones: Insights From NHANES 2007-2010.Mediators of inflammation · 2025Article
- Temporal trends and global burden of urolithiasis: a comparative analysis of incidence, prevalence, mortality, and disability-adjusted life years in China and globally from 1990 to 2021.Frontiers in epidemiology · 2025Article
- Barriers to hydration and dietary sodium reduction for kidney stone prevention: a population-based study with 12-month clinical outcomes.Frontiers in public health · 2025Article
- The global, regional, and national burden of urolithiasis in 204 countries and territories, 2000-2021: a systematic analysis for the Global Burden of Disease Study 2021.EClinicalMedicine · 2024Article
- Mitochondrial dysfunction in kidney stones and relief of kidney stones after reducing mtROS.Urolithiasis · 2024Article
- Applying urinary ultrasound to predict the risk of spontaneous ureteral stone passage: a retrospective cohort study.BMC urology · 2024Article
- Research progress on miR-124-3p in the field of kidney disease.BMC nephrology · 2024Review
- Review
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8 authors at 3 institutions in 1 country.
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Abstract
Introduction: The aim of this study was to explore the chronological trends in clinical features and utilization of healthcare resources for hospitalized patients with urolithiasis in China. Methods: Patients with urolithiasis were extracted from the Hospital Quality Monitoring System, a national database of hospitalized patients in China, based on the International Classification of Diseases, Tenth Revision, codes. Variables including demographic characteristics, comorbidities, treatment modalities for urolithiasis, length of hospital stay, and expenditures were collected and analyzed. Results: Among 79.8 million hospitalized patients, 3.5 million were diagnosed with urolithiasis with an increasing trend (from 3.0% in 2013 to 4.0% in 2018). Most of these patients had upper urinary tract calculi (76.6% in 2013 and 81.7% in 2018). Middle-aged patients (46-65 years) constituted the largest proportion with a stable trend (from 46.9% in 2013 to 48.8% in 2018), while the proportion of older patients (>65 years) showed an increasing trend (from 23.7% in 2013 to 27.4% in 2018). The percentages of gout/hyperuricemia, hypertension, diabetes, and cardiovascular disease among the hospitalized patients with urolithiasis increased steadily, with the sharpest increases in patients from rural areas. Overall, 656,952 patients (18.9%) received surgical interventions for urolithiasis. The proportions of ureteroscopy and extracorporeal shockwave lithotripsy increased steadily during the 6-year study period, with simultaneous decreases in open surgery and percutaneous nephrolithotomy. The median length of hospital stay decreased from 10 days to 8 days. The cost of urolithiasis intervention accounted for 2.0% of the total hospitalization fee in 2013 and increased to 2.7% in 2018. Conclusions: The analysis showed an increasing trend in the percentage of hospitalized patients with urolithiasis, accompanied by an increased percentage of the total hospitalization fee for urolithiasis intervention during the 6-year study period. Based on the increasing trends in the proportion of older patients (>65 years) and percentages of metabolic comorbidities among patients with urolithiasis, an increased burden of urolithiasis on the healthcare system in China is anticipated.
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