ReviewClinical kidney journal2023
Age and the eGFR-dependent risk for adverse clinical outcomes.
Review in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- The influence of hypoxia in predicting COVID-19 mortality in patients with kidney dysfunction on admission in 2 centers in sub-Saharan Africa.Renal failure · 2026Article
- Patients With Mild ADPKD by Kidney Imaging but Low Estimated GFR.Kidney international reports · 2025Article
- Impact of estimated glomerular filtration rate (eGFR) on in-hospital mortality: an age- and HIV status-specific retrospective cohort study in Uganda.BMC nephrology · 2025Observational
- Mediation effect of antithrombin III between chronic renal insufficiency and chronic coronary artery disease in T2DM patients.Endocrine · 2024Article
- Associations between modest reductions in kidney function and adverse outcomes in young adults: retrospective, population based cohort study.BMJ (Clinical research ed.) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the relative risk of kidney failure increases with more severe chronic kidney disease (CKD) independent of age, with older age the absolute risk of kidney failure at a given time horizon becomes smaller. In this article, we first review some epidemiological measures of outcome occurrence (absolute rate or risk) and association (relative measures: difference or ratio of rates or risks). We emphasize that relative measures need to be presented along with absolute measures to be understood and absolute risk is more helpful than absolute rate when making treatment decisions. We then apply these principles to the discussion of the absolute and relative rates or risks of kidney failure and death across categories of estimated glomerular filtration rate and age. Lastly, we discuss the implications of existing studies on whether the definition of CKD should account for age.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.