Evidence map›Paper›PMID 36755713›Full record

ArticleChemical science2023

Chiral adaptive recognition with sequence specificity of aromatic dipeptides in aqueous solution by an achiral cage.

Lin Cheng, Ping Tian, Honghong Duan, Qingfang Li, Xiaowen Song, Anyang Li, Liping Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Dynamic covalent synthesis.Chemical science · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin ChengKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.
Ping TianKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.
Honghong DuanKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.
Qingfang LiKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.
Xiaowen SongKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.
Anyang LiKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.ORCID https://orcid.org/0000-0001-6634-842X
Liping CaoKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, Xi'an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University Xi'an 710069 China chcaoliping@nwu.edu.cn.ORCID https://orcid.org/0000-0002-1747-6107

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequence-specific recognition of peptides and proteins by synthetic compounds or systems remains a huge challenge in biocompatible media. Here, we report the chiral adaptive recognition (CAR) with sequence specificity of aromatic dipeptides in a purely aqueous solution using an achiral tetraphenylethene-based octacationic cage (1) as both a molecular receptor and chiroptical sensor. 1 can selectively bind and dimerize aromatic dipeptides to form 1 : 2 host-guest complexes with high binding affinity (>10

Identifiers

PMID36755713
PMCPMC9890615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.