ArticleEuropean journal of medical research2023
Percutaneous fractionated radiotherapy of the groin to eliminate lymphatic fistulas after vascular surgery.
Article in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Radiotherapy for postoperative groin lymphatic fistulas: A systematic review of clinical outcomes and treatment planning.Clinical and translational radiation oncology · 2026Review
- Occurrence, Definition and Risk Factors Related to Groin Wound Complications Following Open Vascular Surgeries.International wound journal · 2026Article
- Therapy-refractory lymphatic fistulas following complete lymph node dissection in malignant melanoma: local radiotherapy as an effective therapeutic modality to avoid cancer treatment delay.Langenbeck's archives of surgery · 2026Article
- Low-dose radiotherapy for benign conditions: management of persistent inguinal lymphorrea.Radiation oncology (London, England) · 2025Article
- Risk factors for postoperative surgical complications after inguinal lymph node dissection in penile cancer patients.Scientific reports · 2025Article
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Authors and funding
25 authors at 7 institutions in 3 countries.
Funding
Abstract
backgroundVascular surgery of the inguinal area can be complicated by persistent lymphatic fistulas. Rapid and effective treatment is essential to prevent infection, sepsis, bleeding, and possible leg amputation. Current data on irradiation of lymphatic fistulas lack recommendation on the appropriate individual and total dose, the time of irradiation, and the target volume. Presumably, a dose of 0.3-0.5 to 1-12 Gy should be sufficient for the purpose. Currently, radiotherapy is a "can" recommendation, with a level 4 low evidence and a grade C recommendation, according to the DEGRO S2 guidelines. As part of a pilot study, we analyzed the impact and limitations of low-dose radiation therapy in the treatment of inguinal lymphatic fistulas. PATIENTS AND
methodsAs a part of an internal quality control project, patients with lymphatic fistulas irradiated in the groin area after vascular surgery for arterial occlusive disease (AOD) III-IV, repair of pseudo aneurysm or lymph node dissection due to melanoma were selected, and an exploratory analysis on retrospectively collected data performed.
resultsTwelve patients (10 males and 2 females) aged 62.83 ± 12.14 years underwent open vascular reconstruction for stage II (n = 2), III (n = 1), and IV (n = 7) arterial occlusive disease (AOD), lymph node dissection for melanoma (n = 1) or repair of a pseudoaneurysm (n = 1). Surgical vascular access was obtained through the groin and was associated with a persistent lymphatic fistula, secreting more than 50 ml/day. Patients were irradiated five times a week up to a maximum of 10 fractions for the duration of the radiation period. Fraction of 0.4 Gy was applied in the first 7 cases, while 5 patients were treated with a de-escalating dose of 0.3 Gy. There was a resolution of the lymphatic fistula in every patient without higher grade complications.
conclusionLow-dose irradiation of the groin is a treatment option for persistent lymphatic fistula after inguinal vascular surgery.
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