Evidence map›Paper›PMID 36755284›Full record

ArticleChild and adolescent psychiatry and mental health2023

Resilient phenotypes among bereaved youth: a comparison of trajectory, relative, and cross-domain approaches.

Ana Lucia Espinosa Dice, Xian Ye, Stephanie Gyuri Kim, Katie A McLaughlin, Ananda B Amstadter, Henning Tiemeier, Christy A Denckla

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Article in Child and adolescent psychiatry and mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ana Lucia Espinosa DiceDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Xian YeDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Stephanie Gyuri KimHuman Development and Family Studies, University of Illinois Urbana-Champaign, Champaign, IL, USA.
Katie A McLaughlinDepartment of Psychology, Harvard University, Cambridge, MA, USA.
Ananda B AmstadterVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Henning TiemeierDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Christy A DencklaDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA. cdenckla@hsph.harvard.edu.

Funding

Pathogenic mechanisms in post-bereavement psychopathology: Contributions of gene-environment interplay, psychosocial factors, and cognitive ability in two population-based cohortsK23MH117278 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI DENCKLA, CHRISTY ANN · 2019 to 2023
$942k
Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009NIMH NIH HHS 1K23MH117278-01A1
6 · The paper itself

Abstract

backgroundBereavement is a common traumatic event associated with adverse health outcomes across the life course. Despite these risks, not all bereaved individuals experience these negative effects. Limited scientific consensus exists on how to define resilience in individuals who have experienced the death of a loved one.

methodsUsing a sample of N = 3766 youth from the Avon Longitudinal Study of Parents and Children birth cohort, we identified bereavement of a family member between ages 7 and 8.5. We derived and compared three different approaches to assess resilience among bereaved youth. Trajectory-based psychological resilience identified sub-groups with similar psychological symptom profiles between ages 6 and 16 using latent growth mixture models. Relative psychological resilience at age 16 leveraged standardized residuals from a model regressing psychological symptoms on bereavement to determine better-than-expected psychological functioning relative to bereavement status. Relative cross-domain resilience around age 16 was a sum score of the residuals approach applied to eight unique domains of health. Predictive validity of each approach was assessed using depressive symptoms at age 17.5

resultsOverall, N = 877 (23%) youth were bereaved of a family member between ages 7 and 8.5. Using latent growth mixture models, a three-class solution described 84% of bereaved youth with low and stable psychological symptoms over time, 8% with worsening symptoms, and 8% with improving yet elevated symptoms. Each relative resilience score was largely concordant with the trajectory-based approach in identifying individuals as resilient or not, though relative psychological resilience demonstrated a stronger degree of concordance than the cross-domain score. Relative psychological and cross-domain resilience exhibited moderate to low correlation, depending on the domains included (r = 0.14-0.43). For each approach, resilience significantly predicted lower depressive symptoms at age 17.5, highlighting predictive validity of these measures.

conclusionsPsychological symptom trajectories among bereaved youth aligned with those previously identified among bereaved adults. The residual-based approach to defining resilience exhibited limited utility in the context of bereavement. When identifying risk and resilience after bereavement, researchers and clinicians must address the interplay across psychosocial and physical health domains, as bereaved youth considered resilient from a mental health perspective may benefit from intervention in other domains.

Indexed as

ALSPACBereavementChildhood and adolescenceLatent growth mixture modelsResilience

Identifiers

PMID36755284
PMCPMC9909953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.