Evidence map›Paper›PMID 36755197›Full record

ReviewAdvanced biology2023

Catching Our Breath: Updates on the Role of Dendritic Cell Subsets in Asthma.

Jacquelyn D Lajiness, Joan M Cook-Mills

Abstract readReview
In one paragraph

Review in Advanced biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Flavonoids as potential anti-asthmatic agents.Frontiers in immunology · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Multifaceted roles of mitochondria in asthma.Cell biology and toxicology · 2024
    Review
  10. Long-chain acyl-CoA synthetase 4-mediated mitochondrial fatty acid metabolism and dendritic cell antigen presentation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jacquelyn D LajinessDepartment of Pediatrics, Division of Neonatology, Indiana University School of Medicine, 1030 West Michigan Street, Suite C 4600, Indianapolis, IN, 46202-5201, USA.ORCID 0000-0003-3386-6292
Joan M Cook-MillsDepartment of Pediatrics, Department of Microbiology and Immunology, Pediatric Pulmonary, Asthma, and Allergy Basic Research Program, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut Street, R4-202A, Indianapolis, IN, 46202, USA.

Funding

Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
Tocopherol regulation of the development of responsiveness to allergen early in lifeR01AI127695 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI COOK-MILLS, JOAN M · 2017 to 2021
$3.6M
Lipid Regulation of the Development of Responsiveness to Allergen in Neonates and InfantsU01AI131337 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI COOK-MILLS, JOAN M · 2017 to 2021
$2.5M
NIAID NIH HHS R01 AI127695NIAID NIH HHS U01 AI131337NICHD NIH HHS K12 HD000850NIH HHS K12HD000850NIH HHS R01AI127695NIH HHS U01 AI131337
6 · The paper itself

Abstract

Dendritic cells (DCs), as potent antigen presenting cells, are known to play a central role in the pathophysiology of asthma. The understanding of DC biology has evolved over the years to include multiple subsets of DCs with distinct functions in the initiation and maintenance of asthma. Furthermore, asthma is increasingly recognized as a heterogeneous disease with potentially diverse underlying mechanisms. The goal of this review is to summarize the role of DCs and the various subsets therein in the pathophysiology of asthma and highlight some of the crucial animal models shaping the field today. Potential future avenues of investigation to address existing gaps in knowledge are discussed.

Indexed as

AsthmaDendritic CellsAnimalsallergic diseaseasthmaatopic diseasedendritic cellsdendritic cell subsets

Identifiers

PMID36755197
PMCPMC10293089

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.