ArticleScientific reports2023
Three-dimensional visualization of dentine occlusion based on FIB-SEM tomography.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- An Ultrastructural, In-Situ Study on the Impact of Desensitizing Agents on Dentin.International dental journal · 2025Article
- Innovative Damage Assessment of Endodontic Instruments Based on Digital Image Stacking.Clinics and practice · 2024Article
- Tough Cortical Bone-Inspired Tubular Architected Cement-Based Material with Disorder.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Nano-CT characterization of dentinal tubule occlusion in SDF-treated dentin.Scientific reports · 2023Article
- Erosion-inhibiting potential of the stannous fluoride-enriched CPP-ACP complex in vitro.Scientific reports · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The occlusion of dentinal tubules has become a rapid and effective method for treating dentin hypersensitivity. Accurate evaluation of dentin occlusion is critical to illustrate the efficacy of oral care products and to optimize dental therapy in the clinics, which is limited by the conventional two-dimensional (2-D) characterization methods. Here, we demonstrate the visualization of the dentin occlusion via three-dimensional (3-D) characterization using a focused ion beam-scanning electron microscopy (FIB-SEM) tomography. Using the "Slice and View" approach, the material used for occluding dentin tubules is imaged with a very high-resolution voxel (10 nm × 10 nm × 20 nm) from 2-D SEM images and then reconstructed into a 3-D volume, which presents the mode of action of toothpaste for treating dentin hypersensitivity. Meanwhile, quantitative analysis of the depth of occlusion is successfully obtained. This work validates the feasibility of FIB-SEM tomography in the analysis of dentin occlusion within the complicated networks of dentine tubules at the nanoscale, and provides a novel approach to facilitate the research and development of oral care products.
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Registered trials
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