Evidence map›Paper›PMID 36755098›Full record

ArticleNature2023

Dissecting cell identity via network inference and in silico gene perturbation.

Kenji Kamimoto, Blerta Stringa, Christy M Hoffmann, Kunal Jindal, Lilianna Solnica-Krezel, Samantha A Morris

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 433 papers.

0numbers the graph read from it
0cells of the map it votes in
433citing papers in PubMed
84.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

433 citing papers in PubMed, 576 citations in OpenAlex.

  1. Review
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  10. Predictive control of human pancreatic cell fate using a digital model ofbioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
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  18. Charting Endocrine Progenitors Across Species and Organs.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  19. Article
  20. Article

373 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kenji KamimotoDepartment of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0003-3541-4353
Blerta StringaDepartment of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA.
Christy M HoffmannDepartment of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA.
Kunal JindalDepartment of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-6683-9322
Lilianna Solnica-KrezelDepartment of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0003-0983-221X
Samantha A MorrisDepartment of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA. s.morris@wustl.edu.ORCID http://orcid.org/0000-0001-8561-4340
Washington University in St. Louis · US

Funding

Inductive and morphogenetic processes shaping the zebrafish embryonic axesR35GM118179 · NIGMS · WASHINGTON UNIVERSITY · PI LILIANNA SOLNICAKREZEL · 2016 to 2026
$7.4M
DISSECTING THE MECHANISM OF PIONEER TRANSCRIPTION FACTOR-MEDIATED LINEAGE REPROGRAMMINGR01GM126112 · NIGMS · WASHINGTON UNIVERSITY · PI MORRIS, SAMANTHA ANNETTE · 2017 to 2021
$1.6M
NIGMS NIH HHS R01 GM126112NIGMS NIH HHS R35 GM118179
6 · The paper itself

Abstract

Cell identity is governed by the complex regulation of gene expression, represented as gene-regulatory networks

Indexed as

Cell DifferentiationComputer SimulationGene Regulatory NetworksTranscription FactorsAnimalsEmbryonic DevelopmentHematopoiesisHomeodomain ProteinsHumansLIM-Homeodomain ProteinsMesodermMicePhenotypeZebrafishZebrafish ProteinsHomeodomain ProteinsLhx1a protein, zebrafishLIM-Homeodomain Proteinsnoto protein, zebrafishTranscription FactorsZebrafish Proteins

Identifiers

PMID36755098
PMCPMC9946838
OpenAlexW4319591822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.