Evidence map›Paper›PMID 36754984›Full record

ArticleEye (London, England)2023

Incidence of post vitrectomy endophthalmitis in India - A multicentric study by VRSI study Group.

Payal Naresh Shah, Divyansh K Mishra, Mahesh P Shanmugam, Manisha Agarwal, Pradeep Susvar, Alok C Sen, Rajesh Ramanjulu, Vivek Dave, Veerapan Saravanan, Naresh Kannan and 21 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 13 institutions in 1 country.

Payal Naresh ShahSankara Eye Hospital, Bengaluru, Karnataka, India.
Divyansh K MishraSankara Eye Hospital, Bengaluru, Karnataka, India.
Mahesh P ShanmugamSankara Eye Hospital, Bengaluru, Karnataka, India. maheshshanmugam@gmail.com.ORCID 0000-0002-1912-4412
Manisha AgarwalMedical Research Foundation, Chennai, Tamil Nadu, India.
Pradeep SusvarDr Shroff's Charity Eye Hospital, New Delhi, India.ORCID 0000-0002-2414-1794
Alok C SenSadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.ORCID 0000-0003-2374-4187
Rajesh RamanjuluSankara Eye Hospital, Bengaluru, Karnataka, India.
Vivek DaveL V Prasad Eye Institute, Hyderabad, Telangana, India.
Veerapan SaravananAravind Eye Hospital, Coimbatore, Tamil Nadu, India.
Naresh KannanAravind Eye Hospital, Madurai, Tamil Nadu, India.ORCID 0000-0002-3993-9790
Tushar SinhaDisha Eye Hospital, Kolkata, West Bengal, India.
Manavi D SindalAravind Eye Hospital and Postgraduate Institute of Ophthalmology, Pondicherry, India.ORCID 0000-0003-3798-6697
Simar Rajan SinghAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.ORCID 0000-0003-0207-1913
Madhu Kumar RajannaSankara Eye Hospital, Guntur, Andhra Pradesh, India.
Apoorva G AyachitM M Joshi Eye Institute, Hubballi, Karnataka, India.
Aditya MaitrayAravind Eye Hospital, Chennai, Tamil Nadu, India.ORCID 0000-0002-7569-687X
Naresh Kumar YadavNarayana Nethralaya, Bengaluru, Karnataka, India.
Divya BalakrishnanGiridhar Eye Institute, Kochi, Kerala, India.
Eesh NigamAditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.
Ritesh NarulaCentre for Sight, New Delhi, India.
Syed M A KhadarAravind Eye Hospital, Tirunelveli, Tamil Nadu, India.
Neelam AtriShroff Eye Centre, New Delhi, India.
Sangeet MittalThind Eye Hospital, Jalandhar, Punjab, India.
Hemanth MurthyRetina Institute Of Karnataka, Bengaluru, Karnataka, India.
Prabhu Shanker MahalingamSankara eye hospital, Coimbatore, Tamil Nadu, India.
Gopal S PillaiAmrita Institute of Medical Sciences, Kochi, Kerala, India.
Manish NagpalRetina Foundation, Ahmedabad, Gujarat, India.
Jaydeep WalinjkarAditya Jyot Eye Hospital (P) Limited (A Unit Of Dr Agarwals Eye Hospital), Mumbai, Maharashtra, India.
Vishali GuptaAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Abhishek KothariPink city eye and retina center, Jaipur, Rajasthan, India.
VRSI Study Group
Aravind Eye Hospital · INEye Hospital in Bangalore · INDr. Shroff’s Charity Eye Hospital · INPost Graduate Institute of Medical Education and Research · INAditya Jyot Eye Hospital · INAmrita Institute of Medical Sciences and Research Centre · INCentre for Sight · INChaithanya Eye Hospital and Research Institute · INGujarat Kidney Foundation · INJoshi Hospital · INL V Prasad Eye Institute · INNarayana Nethralaya · INSankara Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe incidence of post vitrectomy endophthalmitis (PVE) is reported to be between 0.02 and 0.84%. Resterilization of single use instruments is a common practice amidst developing countries to make it more affordable to the patients by reducing the cost of the surgery and also reduce the environmental hazard. The aim of our study is to evaluate the incidence of PVE amidst existing sterilization practices of reused instruments in multiple vitreoretinal centres in India. METHODOLOGY: Centres with an endophthalmitis tracking system were invited to participate in a survey. Twenty-five centres were sent a questionnaire via email. The questionnaire included details about the institution, number of vitrectomies performed in a year, sterilization practices followed pre-operatively, intraoperatively and postoperatively, incidence of endophthalmitis and instrument reuse policies.

resultsA total of 29 cases of endophthalmitis were reported out of the 47,612 vitrectomies performed across various centres. The mean incidence of endophthalmitis was 0.06%. There was no difference in the rates of endophthalmitis based on various pre-operative, intraoperative or postoperative prophylactic measures. Nearly 80% of the centres change most of the instruments after every case, while the rest reused. The mean number of times a cutter was being reused until discarded was 4.7. Nearly 76% followed a performance-based protocol, and the remaining 24% had a fixed protocol for the number of times an instrument can be reused before discarding it.

conclusionPVE rates are not significantly different in India despite the multiuse of single use instruments. The purpose of this paper is not to suggest an alternate protocol but to creating one in the future with these results in mind, to rationalise the use of single use instruments, make VR surgery more affordable and also have a positive impact on the carbon footprint of consumables in surgery.

Indexed as

EndophthalmitisEye Infections, BacterialHumansIncidenceIndiaPostoperative ComplicationsRetrospective StudiesVitrectomy

Identifiers

PMID36754984
PMCPMC10516918
OpenAlexW4319593314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.