Evidence map›Paper›PMID 36754877›Full record

ArticleNeurosurgical review2023

Microanatomical study of arachnoid granulations and meningeal architecture around Meckel's cave.

Grzegorz Wysiadecki, R Shane Tubbs, Joe Iwanaga, Maciej Radek, Jerzy Walocha, Piotr Brzeziński, Józef Kobos, Michał Polguj

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurosurgical review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Grzegorz WysiadeckiDepartment of Normal and Clinical Anatomy, Chair of Anatomy and Histology, Medical University of Lodz, Ul. Żeligowskiego 7/9, 90-752, Lodz, Poland. grzegorz.wysiadecki@umed.lodz.pl.ORCID http://orcid.org/0000-0003-3631-2295
R Shane TubbsDepartment of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA.ORCID http://orcid.org/0000-0003-1317-1047
Joe IwanagaDepartment of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA.ORCID http://orcid.org/0000-0002-8502-7952
Maciej RadekDepartment of Neurosurgery, Spine and Peripheral Nerve Surgery, Medical University of Lodz, University Hospital WAM-CSW, Lodz, Poland.ORCID http://orcid.org/0000-0003-3544-1482
Jerzy WalochaDepartment of Anatomy, Jagiellonian University Medical College, Cracow, Poland.ORCID http://orcid.org/0000-0001-8587-2315
Piotr BrzezińskiDepartment of Histology and Embryology, Chair of Anatomy and Histology, Medical University of Lodz, Lodz, Poland.ORCID http://orcid.org/0000-0002-5654-5267
Józef KobosDepartment of Histology and Embryology, Chair of Anatomy and Histology, Medical University of Lodz, Lodz, Poland.ORCID http://orcid.org/0000-0001-7197-3334
Michał PolgujDepartment of Normal and Clinical Anatomy, Chair of Anatomy and Histology, Medical University of Lodz, Ul. Żeligowskiego 7/9, 90-752, Lodz, Poland.ORCID http://orcid.org/0000-0003-4146-4998
Medical University of Lodz · PLTulane University · USJagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the microanatomy of Meckel's cave (MC) has been well studied, there are still controversies regarding the meningeal architecture of the space. Moreover, there are only general mentions of the arachnoid granulations near MC in just a few sources. This study is aimed at determining the frequency, location, and anatomical variability of the main clusters of arachnoid granulations around MC. The dissection involved 26 isolated specimens of MC fixed in formalin (neutral buffered, 10%). This number included five freshly harvested specimens examined histologically. Additional paraffin block with MC horizontal section was taken from our neuroanatomical collection. Carefully selected anatomical and histological techniques were applied to assess the complex relationships between the arachnoid granulations and adjacent structures. Arachnoid granulations were found around MC in all specimens with different anatomical variations. The main clusters of arachnoid granulations were close to the trigeminal ganglion and its divisions. The dorsolateral wall of MC was a thick layer formed by interweaving bundles of collagen fibers arranged in various directions. The entire MC was surrounded by a dural sleeve (envelope). This sleeve separated MC from the lateral sellar compartment. At its anterior (rostral) end, it formed a cribriform area pierced by individual fascicles of the trigeminal nerve's primary divisions. The connective tissue forming the sleeve was not only continuous with the epineurium but also shifted to the perineuria surrounding individual nerve fascicles. The meningeal architecture around MC has a complex and multilayer arrangement with a collagenous sleeve closely related to the trigeminal ganglion. Arachnoid granulations are typically found around MC.

Indexed as

DissectionMeningesArachnoidHumansArachnoid granulationsMeckel’s (trigeminal) caveMeningesMicrosurgical anatomySkull baseTrigeminal (Gasserian) ganglionTrigeminal nerve

Identifiers

PMID36754877
PMCPMC9908694
OpenAlexW4319656418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.