Evidence map›Paper›PMID 36754840›Full record

ReviewObesity (Silver Spring, Md.)2023

Sleep variability and regularity as contributors to obesity and cardiometabolic health in adolescence.

Natasha Morales-Ghinaglia, Julio Fernandez-Mendoza

Erratum issuedAbstract readReview
In one paragraph

Review in Obesity (Silver Spring, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  4. Skin-deep resilience in Black youth: Striving and sleep reactivity to daily stress.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  5. Review
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  11. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Natasha Morales-GhinagliaSleep Research & Treatment Center, Department of Psychiatry & Behavioral Health, Penn State University, College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0002-5312-2509
Julio Fernandez-MendozaSleep Research & Treatment Center, Department of Psychiatry & Behavioral Health, Penn State University, College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0001-9584-6161

Funding

Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
The Penn State Child Sleep Cohort: Cardiometabolic and Neurocognitive Risk in Young AdulthoodR01HL136587 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI FERNANDEZ-MENDOZA, JULIO · 2018 to 2022
$3.7M
Sleep Cortical Dynamics and Neurobehavioral Risk in Children and Adolescents: A Longitudinal StudyR01MH118308 · NIMH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI FERNANDEZ-MENDOZA, JULIO · 2019 to 2021
$1.2M
NCATS NIH HHS UL1 TR000127NHLBI NIH HHS R01 HL136587NIMH NIH HHS R01 MH118308
6 · The paper itself

Abstract

objectiveAdolescence is a developmental stage of critical changes in sleep and its circadian timing when the contribution of abnormal sleep variability (amount) and sleep regularity (timing) to obesity and its associated adverse cardiometabolic health outcomes appears to increase. The aim of this study was to summarize findings from studies conducted in adolescents examining both sleep variability and regularity in relation to obesity and cardiometabolic health. Gaps in research and potential causal pathways that future studies should examine are highlighted.

resultsNightly deviations in sleep duration and sleep midpoint appear to contribute to the development of obesity and associated adverse cardiometabolic outcomes in youth. Studies show that increased sleep variability and irregularity are associated with obesity, decreased physical activity, dysregulated eating and inadequate diet, metabolic dysfunction, impaired cardiac autonomic balance, and elevated blood pressure in adolescents.

conclusionsA stable circadian timing of sleep is essential to the overall physical well-being of youth. Emerging evidence supports that sleep variability and circadian misalignment, including sleep irregularity, contribute to adverse obesity-related health outcomes early on in adolescence. Future studies should focus on the underlying behavioral and biological mechanisms in the causal pathway between day-to-day deviations in the amount and timing of sleep and obesity.

Indexed as

Circadian RhythmHypertensionAdolescentHumansObesitySleepSleep Duration

Identifiers

PMID36754840
PMCPMC9975080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.