Evidence map›Paper›PMID 36754751›Full record

ReviewSeminars in cell & developmental biology2023

Generative models of morphogenesis in developmental biology.

Namid R Stillman, Roberto Mayor

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Physical models of embryonic epithelial healing.PLoS computational biology · 2026
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Namid R StillmanDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: n.shatil@ucl.ac.uk.
Roberto MayorDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor; Santiago, Chile Santiago, Chile.. Electronic address: r.mayor@ucl.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/T013044Biotechnology and Biological Sciences Research Council M008517Medical Research Council MR/S007792/1Wellcome TrustWellcome Trust 102489/Z/13/Z
6 · The paper itself

Abstract

Understanding the mechanism by which cells coordinate their differentiation and migration is critical to our understanding of many fundamental processes such as wound healing, disease progression, and developmental biology. Mathematical models have been an essential tool for testing and developing our understanding, such as models of cells as soft spherical particles, reaction-diffusion systems that couple cell movement to environmental factors, and multi-scale multi-physics simulations that combine bottom-up rule-based models with continuum laws. However, mathematical models can often be loosely related to data or have so many parameters that model behaviour is weakly constrained. Recent methods in machine learning introduce new means by which models can be derived and deployed. In this review, we discuss examples of mathematical models of aspects of developmental biology, such as cell migration, and how these models can be combined with these recent machine learning methods.

Indexed as

Computer SimulationDevelopmental BiologyModels, BiologicalMorphogenesisAnimalsCell MovementHumansMachine LearningCell migrationComputational biologyDevelopmental biologyGenerative modelsSimulation-based inference

Identifiers

PMID36754751
PMCPMC10615838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.