Evidence map›Paper›PMID 36754572›Full record

ArticleInternational journal of spine surgery2023

How Much Blood Loss Is Too Much for a 1-Level Open Lumbar Fusion?

Hani Chanbour, Jeffrey W Chen, Steven G Roth, Byron F Stephens, Amir M Abtahi, Scott L Zuckerman

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Article in International journal of spine surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hani Chanbour *Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Jeffrey W Chen *Vanderbilt University, School of Medicine, Nashville, TN, USA.
Steven G RothDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Byron F StephensDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Amir M AbtahiDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Scott L ZuckermanDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA scott.zuckerman@vumc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the known association between increased estimated blood loss (EBL) and suboptimal perioperative outcomes, the exact threshold of EBL that impacts outcomes following elective spine surgery remains unknown. In a cohort of patients undergoing elective 1-level open posterior lumbar fusion, we sought to identify EBL thresholds associated with: (1) prolonged length of stay (LOS), (2) postoperative complications, and (3) patient-reported outcomes (PROs).

methodsA retrospective, single-center study was performed of patients undergoing elective, 1-level open posterior lumbar fusion with and without interbody fusion between October 2010 and April 2021. The primary exposure variable was EBL. Primary outcomes included: (1) LOS, (2) 30-day complications, and (3) 3-month PROs. Minimum clinically important difference was set at 30% improvement from baseline. For purposes of receiver-operating characteristic curves, LOS was dichotomized as 1 vs ≥2 days.

resultsOf the 2028 patients undergoing posterior lumbar fusion surgery, 1183 underwent 1-level fusions, 763 (64.5%) with interbody fusion and 420 (35.5%) without.

conclusionsIn patients undergoing 1-level posterior lumbar fusion, EBL volumes greater than 275 and 238 mL in patients with and without interbody fusion, respectively, were associated with increased LOS beyond POD1. No effect was found regarding 30-day complications and 3-month PROs. Although EBL did not directly impact complications or PROs, surgeons may expect longer LOS when higher EBL is reported. CLINICAL RELEVANCE: EBL above 275 mL with an interbody and 238 mL without an interbody were associated with prolonged LOS beyond POD1 in 1-level open lumbar fusion. LEVEL OF EVIDENCE: 3:

Indexed as

estimated blood lossinterbody fusionlength of staypatient-reported outcomesposterior lumbar fusion

Identifiers

PMID36754572
PMCPMC10025837

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.