ArticleJournal of the American College of Cardiology2023
Acute Cardiac Events During COVID-19-Associated Hospitalizations.
Article in Journal of the American College of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 36 citations in OpenAlex.
- Myocardial and Vascular Involvement in COVID-19 and Post-Vaccination States: Understanding Injury Pathways and Clinical Implications.Life (Basel, Switzerland) · 2026Review
- Non-Ischemic Pattern of LGE After COVID-19 Correlates More with Severity of Acute Illness than with Long-Term Myocardial Dysfunction.Journal of clinical medicine · 2025Article
- Article
- Cardiac Events in Adults Hospitalized for Respiratory Syncytial Virus vs COVID-19 or Influenza.JAMA network open · 2025Article
- Observational
- Costs and Healthcare Utilization of Heart Disease by COVID-19 Diagnosis and Race and Ethnicity.AJPM focus · 2025Article
- Trends in COVID-19-Attributable Hospitalizations Among Adults With Laboratory-Confirmed SARS-CoV-2-COVID-NET, June 2020 to September 2023.Influenza and other respiratory viruses · 2024Article
- Pathogenic mechanisms of cardiovascular damage in COVID-19.Molecular medicine (Cambridge, Mass.) · 2024Review
- The Impact of Cardiovascular Antecedents on the Prognosis of COVID-19 Critically Ill Patients.Journal of clinical medicine · 2024Article
- Trends in Cardiovascular Disease Mortality Rates and Excess Deaths, 2010-2022.American journal of preventive medicine · 2024Article
- Pathological Interplay and Clinical Complications between COVID-19 and Cardiovascular Diseases: An Overview in 2023.Cardiology · 2024Review
- Interatrial Block and Electrocardiographic Markers of Repolarization in Patients Hospitalized with COVID-19: Classical and Bayesian Analysis.Medeniyet medical journal · 2023Article
- COVID Vaccination as a Strategy for Cardiovascular Disease Prevention.Current cardiology reports · 2023Review
- Lessons From the COVID-19 Pandemic: Updating Our Approach to Masking in Health Care Facilities.Annals of internal medicine · 2023Article
- Acute Cardiovascular Complications of COVID-19: The High Risk of Underlying Heart Disease.Journal of the American College of Cardiology · 2023Article
- COVID-19 and the cardiovascular system: a study of pathophysiology and interpopulation variability.Frontiers in microbiology · 2023Review
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26 authors at 14 institutions in 1 country.
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Abstract
backgroundCOVID-19 is associated with cardiac complications.
objectivesThe purpose of this study was to estimate the prevalence, risk factors, and outcomes associated with acute cardiac events during COVID-19-associated hospitalizations among adults.
methodsDuring January 2021 to November 2021, medical chart abstraction was conducted on a probability sample of adults hospitalized with laboratory-confirmed SARS-CoV-2 infection identified from 99 U.S. counties in 14 U.S. states in the COVID-19-Associated Hospitalization Surveillance Network. We calculated the prevalence of acute cardiac events (identified by International Classification of Diseases-10th Revision-Clinical Modification codes) by history of underlying cardiac disease and examined associated risk factors and disease outcomes.
resultsAmong 8,460 adults, 11.4% (95% CI: 10.1%-12.9%) experienced an acute cardiac event during a COVID-19-associated hospitalization. Prevalence was higher among adults who had underlying cardiac disease (23.4%; 95% CI: 20.7%-26.3%) compared with those who did not (6.2%; 95% CI: 5.1%-7.6%). Acute ischemic heart disease (5.5%; 95% CI: 4.5%-6.5%) and acute heart failure (5.4%; 95% CI: 4.4%-6.6%) were the most prevalent events; 0.3% (95% CI: 0.1%-0.5%) experienced acute myocarditis or pericarditis. Risk factors varied by underlying cardiac disease status. Patients with ≥1 acute cardiac event had greater risk of intensive care unit admission (adjusted risk ratio: 1.9; 95% CI: 1.8-2.1) and in-hospital death (adjusted risk ratio: 1.7; 95% CI: 1.3-2.1) compared with those who did not.
conclusionsAcute cardiac events were common during COVID-19-associated hospitalizations, particularly among patients with underlying cardiac disease, and are associated with severe disease outcomes. Persons at greater risk for experiencing acute cardiac events during COVID-19-associated hospitalizations might benefit from more intensive clinical evaluation and monitoring during hospitalization.
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