Evidence map›Paper›PMID 36754373›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2023

Association of Fruit and Vegetable Consumption With Mild Cognitive Impairment in Low- and Middle-Income Countries.

Lee Smith, Guillermo F López Sánchez, Nicola Veronese, Pinar Soysal, Hans Oh, Karel Kostev, Masoud Rahmati, Laurie Butler, Poppy Gibson, Helen Keyes and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Mild Cognitive Impairment and Suicidal Ideation Among Adults Aged 65 Years or Older From Low- and Middle-Income Countries.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 8 countries.

Lee SmithCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Guillermo F López SánchezDivision of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain.ORCID 0000-0002-9897-5273
Nicola VeroneseDepartment of Internal Medicine, Geriatrics Section, University of Palermo, Palermo, Italy.
Pinar SoysalDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.ORCID 0000-0002-6042-1718
Hans OhSuzanne Dworak Peck School of Social Work, University of Southern California, Los Angeles, California, USA.
Karel KostevUniversity Clinic of Marburg, Marburg, Germany.ORCID 0000-0002-2124-7227
Masoud RahmatiDepartment of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Iran.ORCID 0000-0003-4792-027X
Laurie ButlerCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Poppy GibsonFaculty of Education and Social Care, Anglia Ruskin University, Chelmsford, UK.
Helen KeyesSchool of Psychology and Sport Science, Anglia Ruskin University, Cambridge, UK.
Yvonne BarnettCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, South Korea.ORCID 0000-0003-2326-1820
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain.
Anglia Ruskin University · GBBezmiâlem Vakıf Üniversitesi · TRInstitució Catalana de Recerca i Estudis Avançats · ESLorestan University · IRPhilipps University of Marburg · DEUniversidad de Murcia · ESUniversity of Palermo · ITUniversity of Southern California · USYonsei University · KR

Funding

Towards improving the measurement of health and disability trends, the compressioR01AG034479 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH · 2010 to 2014
$5.3M
Harmonizing health outcomes and determinants across longitudinal studies on agingR21AG034263 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH, KOWAL, PAUL R. · 2011 to 2012
$255k
NIA NIH HHS R01 AG034479NIA NIH HHS R21 AG034263NIA NIH HHS Y1 AG1005-01
6 · The paper itself

Abstract

backgroundInadequate fruit and vegetable intake may be associated with cognitive decline but its association with mild cognitive impairment (MCI; a preclinical stage of dementia) is largely unknown. Therefore, we examined the association of fruit and vegetable consumption with MCI among middle-aged and older adults from low- and middle-income countries (LMICs).

methodsCross-sectional, nationally representative data from the WHO Study on global AGEing and adult health were analyzed. MCI was defined using the National Institute on Aging-Alzheimer's Association criteria. Quintiles of vegetable and fruit consumption were created based on the number of servings consumed on a typical day. Multivariable logistic regression analysis was conducted.

resultsData on 32 715 individuals aged ≥50 years were analyzed (mean [standard deviation] age 62.1 [15.6] years; 51.7% females). Greater fruit consumption was dose-dependently associated with lower odds for MCI. For example, the highest quintile (vs lowest) had 47% lower odds for MCI (odds ratio [OR] = 0.53; 95% confidence interval [CI] = 0.43-0.66). For vegetable consumption, compared to the lowest quintile, the second to fourth quintiles had significant 38%-44% lower odds for MCI but there was no significant difference for the highest quintile (OR = 0.82; 95% CI = 0.59-1.15).

conclusionsHigher fruit and vegetable consumption was associated with lower odds for MCI among middle-aged and older adults from LMICs, but no significant differences were found between the highest and lowest quintiles of vegetable consumption. Future longitudinal studies are required to explore these findings in more depth, and mechanistic studies are required to elucidate on the observed possible U-shaped association between vegetable consumption and MCI.

Indexed as

Cognitive DysfunctionVegetablesAgedCross-Sectional StudiesDeveloping CountriesDietFemaleFruitHumansMaleMiddle AgedDementiaFruitsLow- and middle-income countriesMild cognitive impairmentNutrition

Identifiers

PMID36754373
PMCPMC10848221
OpenAlexW4319455641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.